A5VL03

PR
Gene name
argS
Protein name
Arginine--tRNA ligase
Names
Arginyl-tRNA synthetase, ArgRS
Species
Limosilactobacillus reuteri (strain DSM 20016) (Lactobacillus reuteri)
KEGG Pathway
lre:Lreu_1270
EC number
6.1.1.19: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

73-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5VL03

Entry ID Method Resolution Chain Position Source
AF-A5VL03-F1 Predicted AlphaFoldDB

No variants for A5VL03

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5VL03

No associated diseases with A5VL03

3 regional properties for A5VL03

Type Name Position InterPro Accession
domain Arginyl tRNA synthetase N-terminal domain 1 - 83 IPR005148
domain DALR anticodon binding 449 - 562 IPR008909
domain Arginyl-tRNA synthetase, catalytic core domain 93 - 433 IPR035684

Functions

Description
EC Number 6.1.1.19 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
arginine-tRNA ligase activity Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
arginyl-tRNA aminoacylation The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDKQQVAAA LAQALPEMDV KEIEAKIERP KDSSNGDYAF PTFFLAKTLH KAPQMIASEL
70 80 90 100 110 120
VEKVDQNGFE KVVVAGPYIN FFLDKAQVGA KILQTILADP EHYGEIDLGH QSNVTIDYSS
130 140 150 160 170 180
PNIAKPMGMG HLRSTMIGEA VARILEKVNY NLIRIDYLGD WGTQFGKLMA AYEMWGDEAE
190 200 210 220 230 240
VKKDPINTLL KYYVRINNEA DEHPEYTEAG RNWFAKLEHG DEEAWRLWHW FREVSLERFQ
250 260 270 280 290 300
RVYKMLDVNF DSFNGEAFSA QKMEEPIQLL RDKDLLKPSR GAEIVDLDEY NLPPLLIIKS
310 320 330 340 350 360
NGTTTYITRD LATALFRKRM YGHAKSLYVV GAEQETYFKQ LRAALKEMGF NWWDQIEHIS
370 380 390 400 410 420
FGLMNLNGKK MSTRKGNVVS LEDVLNDSID LARKQIAEKN PDLENADEVA KEVGVGAVIF
430 440 450 460 470 480
HDLKNYRRNA VNFKLEDVVK FEGETGPYVQ YARARAESIL RKGGIRDFSD VDLTKAGAEA
490 500 510 520 530 540
WELISFLGQY SEAIKRAALN YDPSVIAKYA LELAKKFNQY YAHTRILDKD EAQPARLALT
550 560
QAVSDVLKSA LDLLDIKAPD EM