A5V9S7

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Rhizorhabdus wittichii (strain DSM 6014 / CCUG 31198 / JCM 15750 / NBRC 105917 / EY 4224 / RW1) (Sphingomonas wittichii)
KEGG Pathway
swi:Swit_2687
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

800-912 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5V9S7

Entry ID Method Resolution Chain Position Source
AF-A5V9S7-F1 Predicted AlphaFoldDB

No variants for A5V9S7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5V9S7

No associated diseases with A5V9S7

9 regional properties for A5V9S7

Type Name Position InterPro Accession
domain Helicase, C-terminal 424 - 621 IPR001650
conserved_site SEC-C motif 893 - 910 IPR004027
domain SecA DEAD-like, N-terminal 6 - 389 IPR011115
domain SecA Wing/Scaffold 612 - 822 IPR011116
domain SecA, preprotein cross-linking domain 228 - 345 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 248 IPR014001
domain SecA motor DEAD 3 - 613 IPR014018
conserved_site SecA conserved site 487 - 502 IPR020937
domain SecA, C-terminal helicase domain 407 - 583 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGGLAKAIF GSSNDRYVKS LRPILQKIAG FEPTLEAMND EELAAQTVKF RQRLDAGETL
70 80 90 100 110 120
DSLLPEAFAT VREAARRVLG QRHYDVQMIG GIVLHRGEIA EMRTGEGKTL VATLAVYLNA
130 140 150 160 170 180
LPGEGVHVVT VNDYLATRDA EWMGRVYRFL GLTVGVIVPN LSDQERRDAY GADITYGTNN
190 200 210 220 230 240
EFGFDYLRDN MKYDRALMVH RPFNFAVVDE VDSVLIDEAR TPLIISGPTD DKSELYMQVD
250 260 270 280 290 300
AIVKQVTKDD YEFDEKQRSV VLTEDGTERI ERLLEAAGLL EGGNLYAYEN TQVVHHLNQA
310 320 330 340 350 360
LRANVAFKRD TDYIVKDEKI IIIDEFTGRM MDGRRWSDGL HQAVEAKEGV KIEPENQTLA
370 380 390 400 410 420
SITFQNYFRM YPKLGGMTGT AATEAHEFYQ IYKMNVVTIP TNLPVKRIDQ DDEFYKNMLD
430 440 450 460 470 480
KFAAITQAIR EAKERGQPVL VGTVSIEKSE LLSEFLTKEK VEHKVLNARY HEQEAHIVAQ
490 500 510 520 530 540
AGRLGAVTIA TNMAGRGTDI QLGGNLEFRM LDEHPALEIG TPEFDAAAER IRGEIIAEKE
550 560 570 580 590 600
AVLAAGGLFV LGTERHESRR IDNQLRGRSG RQGDPGLSRF YLSLDDDLLR IFGPQTMFAR
610 620 630 640 650 660
MMNKNLADGE AIVSPWISKA IETAQKKVEA RNYDIRKQVV EYDDVMNDQR KVIYEQRADI
670 680 690 700 710 720
MDAETVDDVV TDMRADTANA IVGGCCPPHS YPEQWDVDTL KLRSAETLGI TPPFDEWIEQ
730 740 750 760 770 780
DGIDPEILAE KVLAEADAVI AAKRATIDDQ SWHGIEKSVL LQTLDHHWKE HLATLDALRQ
790 800 810 820 830 840
VIHLRAYAQK TPINEYKHEA FALFERMLVA IREEVTRVLA HVRFEMAPQD YAELPPMPDF
850 860 870 880 890 900
VTEHVNALTG EDNSGDRDGG TLGIIGSRVP QAIAAPAGDD FEITPEIAAT LGRNSLCPCG
910
SGRKYKHCHG AL