A5UX78

PR
Gene name
pyrB
Protein name
Aspartate carbamoyltransferase
Names
Aspartate transcarbamylase, ATCase
Species
Roseiflexus sp (strain RS-1)
KEGG Pathway
rrs:RoseRS_2863
EC number
2.1.3.2: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-45 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5UX78

Entry ID Method Resolution Chain Position Source
AF-A5UX78-F1 Predicted AlphaFoldDB

No variants for A5UX78

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5UX78

No associated diseases with A5UX78

2 regional properties for A5UX78

Type Name Position InterPro Accession
domain Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 164 - 314 IPR006131
domain Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 15 - 157 IPR006132

Functions

Description
EC Number 2.1.3.2 Carboxy- and carbamoyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
amino acid binding Binding to an amino acid, organic acids containing one or more amino substituents.
aspartate carbamoyltransferase activity Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate.

3 GO annotations of biological process

Name Definition
'de novo' pyrimidine nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
'de novo' UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVPAEAGKR RDRRRHVLDL DDFSTQEIEE ILETAVSMKE VLGRAIKQVP TLRGKTIVNM
70 80 90 100 110 120
FFEESTRTRI SFELAGKALS ANVVNFTARG SSVEKGESLI DTVRTLQALG ADMLVMRHSE
130 140 150 160 170 180
SGAPYLAAQY FHGSVINAGD GRHAHPTQAL LDLFTVRQRL GRIEGLKVVI VGDILHSRVA
190 200 210 220 230 240
RSNLWGFTRM GASVTLCAPQ TLIGPESFWK ATWPDLTITS NLDECIKDAD VIMTLRLQKE
250 260 270 280 290 300
RMEAGLLPSL REYSRFFAIT AERVARAAPH CLVMHPGPMN EGVEIMPDVA TSAQSVIEEQ
310
VANGVAVRMA LLYRLSGE