A5UK79
Gene name |
dcd |
Protein name |
dCTP deaminase, dUMP-forming |
Names |
Bifunctional dCTP deaminase:dUTPase, DCD-DUT |
Species |
Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS) |
KEGG Pathway |
msi:Msm_0402 |
EC number |
3.5.4.30: In cyclic amidines |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A5UK79
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A5UK79-F1 | Predicted | AlphaFoldDB |
No variants for A5UK79
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A5UK79 | |||||
No associated diseases with A5UK79
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.4.30 | In cyclic amidines |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| dCTP deaminase (dUMP-forming) activity | Catalysis of the reaction: dCTP + 2 H(2)O = diphosphate + dUMP + H(+) + NH(4)(+). |
| dCTP deaminase activity | Catalysis of the reaction: dCTP + H2O = dUTP + NH3. |
| nucleotide binding | Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| dUMP biosynthetic process | The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate). |
| dUTP biosynthetic process | The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAILSDKTIK | EYLEEGKIVI | DPLKDEQQIQ | PSSVDMRLGD | EFKVFKVIRK | PYIDPKDEED |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IAEYMESSTV | PEGEAFIIHP | NEFALATTQE | YVKVPDDLVA | RVEGRSSMGR | LGVTMHVTAG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YVDPGFEGRI | TLEISNIGAM | PVALYPGQRV | CQLVFETMTT | PAELPYGHPK | RNSKYMKQLK |
| 190 | |||||
| PESSRVKLDY | ELKK |