A5U027

PR
Gene name
mmaA4 (MRA_0653)
Protein name
Hydroxymycolate synthase MmaA4
Names
Mycolic acid methyltransferase, MA-MT, S-adenosylmethionine-dependent methyltransferase, AdoMet-MT, SAM-MT
Species
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
KEGG Pathway
mra:MRA_0653
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5U027

Entry ID Method Resolution Chain Position Source
AF-A5U027-F1 Predicted AlphaFoldDB

No variants for A5U027

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5U027

No associated diseases with A5U027

No regional properties for A5U027

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A5U027

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.

2 GO annotations of biological process

Name Definition
lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
methylation The process in which a methyl group is covalently attached to a molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTRMAEKPIS PTKTRTRFED IQAHYDVSDD FFALFQDPTR TYSCAYFEPP ELTLEEAQYA
70 80 90 100 110 120
KVDLNLDKLD LKPGMTLLDI GCGWGTTMRR AVERFDVNVI GLTLSKNQHA RCEQVLASID
130 140 150 160 170 180
TNRSRQVLLQ GWEDFAEPVD RIVSIEAFEH FGHENYDDFF KRCFNIMPAD GRMTVQSSVS
190 200 210 220 230 240
YHPYEMAARG KKLSFETARF IKFIVTEIFP GGRLPSTEMM VEHGEKAGFT VPEPLSLRPH
250 260 270 280 290 300
YIKTLRIWGD TLQSNKDKAI EVTSEEVYNR YMKYLRGCEH YFTDEMLDCS LVTYLKPGAA
A