A5PK43
Gene name |
ERAL1 |
Protein name |
GTPase Era, mitochondrial |
Names |
ERA-like protein 1 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:523344 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A5PK43
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A5PK43-F1 | Predicted | AlphaFoldDB |
54 variants for A5PK43
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs434457408 | 59 | S>P | No | EVA | |
| rs453057478 | 64 | N>T | No | EVA | |
| rs471406560 | 67 | N>T | No | EVA | |
| rs432291983 | 71 | D>V | No | EVA | |
| rs457083021 | 73 | F>S | No | EVA | |
| rs475459818 | 74 | L>R | No | EVA | |
| rs440467676 | 78 | Q>H | No | EVA | |
| rs473527842 | 78 | Q>P | No | EVA | |
| rs459131629 | 81 | N>T | No | EVA | |
| rs477589881 | 82 | S>L | No | EVA | |
| rs444607201 | 83 | L>F | No | EVA | |
| rs463255359 | 84 | P>L | No | EVA | |
| rs448814789 | 87 | V>A | No | EVA | |
| rs1116612318 | 115 | R>Q | No | EVA | |
| rs476937060 | 117 | V>A | No | EVA | |
| rs450495150 | 128 | T>P | No | EVA | |
| rs443960217 | 138 | V>L | No | EVA | |
| rs481151967 | 143 | K>R | No | EVA | |
| rs448285377 | 146 | H>N | No | EVA | |
| rs460278621 | 146 | H>Q | No | EVA | |
| rs445950077 | 162 | Q>P | No | EVA | |
| rs464414498 | 163 | V>A | No | EVA | |
| rs474099806 | 210 | W>G | No | EVA | |
| rs441209440 | 233 | L>R | No | EVA | |
| rs459568977 | 237 | K>M | No | EVA | |
| rs449436261 | 242 | K>Q | No | EVA | |
| rs468061891 | 251 | T>P | No | EVA | |
| rs133187160 | 261 | G>S | No | EVA | |
| rs451431275 | 276 | T>A | No | EVA | |
| rs451431275 | 276 | T>P | No | EVA | |
| rs476301867 | 277 | H>P | No | EVA | |
| rs437002423 | 281 | P>T | No | EVA | |
| rs455491335 | 297 | M>L | No | EVA | |
| rs474145799 | 299 | W>G | No | EVA | |
| rs471616148 | 303 | Q>H | No | EVA | |
| rs459630785 | 303 | Q>P | No | EVA | |
| rs438711692 | 307 | M>L | No | EVA | |
| rs463707734 | 311 | L>P | No | EVA | |
| rs482334241 | 318 | T>S | No | EVA | |
| rs444885630 | 321 | Q>E | No | EVA | |
| rs482026035 | 322 | Y>S | No | EVA | |
| rs448963966 | 324 | L>M | No | EVA | |
| rs467391638 | 325 | A>E | No | EVA | |
| rs434565604 | 326 | Q>P | No | EVA | |
| rs526140605 | 328 | R>G | No | EVA | |
| rs518189339 | 328 | R>P | No | EVA | |
| rs452952581 | 334 | F>L | No | EVA | |
| rs465131281 | 335 | H>Q | No | EVA | |
| rs432228573 | 338 | V>A | No | EVA | |
| rs457315778 | 339 | L>H | No | EVA | |
| rs442754800 | 342 | Q>H | No | EVA | |
| rs1117677542 | 368 | V>I | No | EVA | |
| rs481869052 | 408 | I>L | No | EVA | |
| rs109619550 | 412 | A>T | No | EVA |
No associated diseases with A5PK43
4 regional properties for A5PK43
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrial matrix | The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| ribosomal small subunit binding | Binding to a small ribosomal subunit. |
| rRNA binding | Binding to a ribosomal RNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ribosomal small subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAASSWRGAV | LLRTVSGLWQ | AGPDAAREWM | TRLPSLLGFQ | QRCVSCVAGP | AFSGPRLASA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SRPNGQNSAL | DCFLGLSQPD | NSLPFRVPAV | SVHRDEQDLL | LVHRPDMPEN | PRVLRVVLLG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| APNAGKSTLS | NQLLGRKVFP | VSKKVHTTRS | QALGVITEKE | TQVILLDTPG | LISPAKQKRH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HLELSLLEDP | WKSMESADLV | VVLVDVSDKW | TRNQLSPQVL | RCLTQFSQVP | SILVMNKVDC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LKQKSVLLEL | TAALTEGVVN | GKKLKTKQAL | RSRPDTHCPS | PAAQGPNPQP | VRDPQQMGWP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HFQEIFMLSA | LSQEDVKTLK | QYLLAQARPG | PWEFHSEVLT | SQTPEEICAN | MIREKLLEYL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PEEVPYNVQQ | KTVVWDEGPS | GELVIEQKLL | VSKESHMKIL | IGPKGYLIAQ | IAQEVGRDLM |
| 430 | |||||
| NIFLCEVQLR | LSVKLLK |