A5N842
Gene name |
infB |
Protein name |
Translation initiation factor IF-2 |
Names |
|
Species |
Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) |
KEGG Pathway |
ckl:CKL_1431 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A5N842
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A5N842-F1 | Predicted | AlphaFoldDB |
No variants for A5N842
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A5N842 | |||||
No associated diseases with A5N842
6 regional properties for A5N842
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 193 - 362 | IPR000795 |
| domain | Small GTP-binding protein domain | 196 - 352 | IPR005225 |
| domain | Translation initiation factor IF-2, N-terminal | 1 - 49 | IPR006847-1 |
| domain | Translation initiation factor IF-2, N-terminal | 116 - 165 | IPR006847-2 |
| domain | Translation initiation factor IF- 2, domain 3 | 470 - 583 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 370 - 463 | IPR044145 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKIRIYELA | KELNISSKKL | ITLLLEEFGV | EVKNHMSVIE | EEDADLIKEF | IEENEDKEEY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LEDKYKNLPE | EKSEKFKKNA | GNTVKIADKN | KSKQDKAVKD | LNEQVSKENH | KVEIEDTITV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KEFSEKIGKP | ITEVIKQLIF | MGVMAAINQE | IDFSTAEKLG | EKFDITVLKK | KEDIDKGVAE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QDEDEDEDTN | VEKRPPVVTV | MGHVDHGKTS | LLDAIRKSKV | TATEAGGITQ | HIGAYTVTIN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GEKITFLDTP | GHEAFTAMRA | RGAQITDIVI | LVVAADDGIM | PQTAEAINHC | KAANVPIVVA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| INKIDRPGAN | VDKVKQELTE | YQLVPEDWGG | DTICIPVSAH | TKEGIDTLLE | MVLLTAEMQE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LKANSNRNGK | GTVVEAKLDK | GRGAVATLLI | QNGTLSVGDS | IIVGSTYGRI | RAMFDDKGNK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IKSAGPSIPV | EILGLSEVPA | AGDRFHQVKD | EKTARDIAEK | RKQKIREEYL | QSTHKVSLED |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LYNQIKEGKV | KELNIIVKAD | VQGSIEALKQ | SLQKLSNEEV | KVRVIHGAVG | AITETDVTLA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SASNAIIIGF | NVRPDSNAQA | AAEKESVDVK | TYRVIYNAIE | DIKAAMVGML | EPDYKEVILG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KAEIRQIYKI | SNIGTIAGCY | VQEGKMVRNC | KVRIIRDGIV | IFESELASLK | RFKDDVKEAA |
| 670 | 680 | 690 | |||
| EGYECGLSIE | KFNDIKEGDI | VEAYDIEEIK | KKEL |