A5JTM5
Gene name |
|
Protein name |
4-chlorobenzoyl coenzyme A dehalogenase |
Names |
4-CBA-CoA dehalogenase, 4-CBCoA dehalogenase, 4-chlorobenzoyl-CoA dehalogenase |
Species |
Pseudomonas sp (strain CBS-3) |
KEGG Pathway |
ag:ABQ44578 |
EC number |
3.8.1.7: In C-halide compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for A5JTM5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1JXZ | X-ray | 190 A | A/B/C | 1-269 | PDB |
| 1NZY | X-ray | 180 A | A/B/C | 1-269 | PDB |
| AF-A5JTM5-F1 | Predicted | AlphaFoldDB |
No variants for A5JTM5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A5JTM5 | |||||
No associated diseases with A5JTM5
1 regional properties for A5JTM5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Eukaryotic translation initiation factor 4E (eIF-4E), conserved site | 96 - 119 | IPR019770 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.8.1.7 | In C-halide compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 4-chlorobenzoyl-CoA dehalogenase activity | Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| coenzyme A metabolic process | The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYEAIGHRVE | DGVAEITIKL | PRHRNALSVK | AMQEVTDALN | RAEEDDSVGA | VMITGAEDAF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CAGFYLREIP | LDKGVAGVRD | HFRIGALWWH | QMIHKIIRVK | RPVLAAINGV | AAGGGLGISL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ASDMAICADS | AKFVCAWHTI | GIGNDTATSY | SLARIVGMRR | AMELMLTNRT | LYPEEAKDWG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LVSRVYPKDD | FREVAWKVAR | ELAAAPTHLQ | VMAKERFHAG | WMQPVEECTE | FEIQNVIASV |
| 250 | 260 | ||||
| THPHFMPCLT | EFLDGHRADR | PQVELPAGV |