A5IT63
Gene name |
gcvPB |
Protein name |
Probable glycine dehydrogenase (decarboxylating) subunit 2 |
Names |
Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2 |
Species |
Staphylococcus aureus (strain JH9) |
KEGG Pathway |
saj:SaurJH9_1593 |
EC number |
1.4.4.2: With a disulfide as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A5IT63
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A5IT63-F1 | Predicted | AlphaFoldDB |
No variants for A5IT63
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A5IT63 | |||||
No associated diseases with A5IT63
1 regional properties for A5IT63
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aminotransferase class V domain | 160 - 280 | IPR000192 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.4.4.2 | With a disulfide as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| glycine dehydrogenase (decarboxylating) activity | Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glycine decarboxylation via glycine cleavage system | The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSKSSPLIF | ERSREGRYAY | SLPKSDIKTN | SVESLLDDKF | IRKNKAEFPE | VAELDLVRHY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TELSNKNFGV | DNGFYPLGSC | TMKYNPKINE | KVARIPGFSE | SHPLQDEDQV | QGSLEIIYSL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QEELKEITGM | DEVTLQPAAG | AHGEWTALMI | FKAYHENNGE | GHRDEVIVPD | SAHGTNPASA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SFAGFKSVTV | KSNERGEVDI | DDLKRVVNEN | TAAIMLTNPN | TLGIFEKNIM | EIREIVHNAG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GLLYYDGANL | NAIMDKVRPG | DMGFDAVHLN | LHKTFTGPHG | GGGPGSGPVG | VVKELASYLP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KPMVIKDGDK | FKYDNDIKNS | IGRVKPFYGN | FGIYLRAYTY | IRTMGATGLK | EVSEAAVLNA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NYIKARLSEH | FEIPYKQYCK | HEFVLSGVRQ | KEFGVRTLDM | AKRLLDFGVH | PPTIYFPLNV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EEGMMIEPTE | TESKETLDYF | IDTLISIAEE | AKNDPDKVLE | APHTTVIDRL | DEATAARKPI |
| LKFENLKQEK |