A5IH19

PR
Gene name
pdxH
Protein name
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Names
PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase
Species
Legionella pneumophila (strain Corby)
KEGG Pathway
lpc:LPC_2766
EC number
1.4.3.5: With oxygen as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5IH19

Entry ID Method Resolution Chain Position Source
AF-A5IH19-F1 Predicted AlphaFoldDB

No variants for A5IH19

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5IH19

No associated diseases with A5IH19

3 regional properties for A5IH19

Type Name Position InterPro Accession
domain Pyridoxamine 5'-phosphate oxidase, putative 34 - 118 IPR011576
domain Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal 172 - 212 IPR019576
conserved_site Pyridoxamine 5'-phosphate oxidase, conserved site 182 - 195 IPR019740

Functions

Description
EC Number 1.4.3.5 With oxygen as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
pyridoxamine-phosphate oxidase activity Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide.

1 GO annotations of biological process

Name Definition
pyridoxine biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKFRSLADI RRDYGELQLS EESAENDPIS QFKLWFDDVL LNEKNDPTAM VLSTVDEKGY
70 80 90 100 110 120
PDSRVVLLKG LENGNFIFYT NYQSAKAMQI QKNPYAALNF YWPQMARQVR VRGRVKKISS
130 140 150 160 170 180
EQSDAYFSSR PLKSQFSAIV SPQSQEILDR ISLEDALNQL IEEYGQKPVV RPENWGGYMI
190 200 210
IPDEIEFWQG RDNRLHDRIH YYRHGHEWTH RRLAP