A5GDA7

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Geotalea uraniireducens (strain Rf4) (Geobacter uraniireducens)
KEGG Pathway
gur:Gura_0231
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5GDA7

Entry ID Method Resolution Chain Position Source
AF-A5GDA7-F1 Predicted AlphaFoldDB

No variants for A5GDA7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5GDA7

No associated diseases with A5GDA7

3 regional properties for A5GDA7

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 283 - 292 IPR020557
domain Fumarate lyase, N-terminal 15 - 308 IPR022761
domain Argininosuccinate lyase, C-terminal 371 - 443 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKDKLWGGR FTQPTDKFVE EFTASIDFDK RLYHQDIRGS IAHARMLGKQ KIIPMADVEK
70 80 90 100 110 120
IVQGLQEILA QIEAGTFDFS ISLEDIHMNI ESRLSAKIGE AGKRLHTGRS RNDQVALDIR
130 140 150 160 170 180
LYLRDELVEI SAYLELLIDS LIFQAEKNID VIMPGYTHLQ TAQPILFAHH MLAYVEMFKR
190 200 210 220 230 240
DIGRIEDCLK RANVLPLGAG ALAGTTFPID REHVAELLDF PAVTRNSLDS VSDRDFALEF
250 260 270 280 290 300
LADASILMMH LSRFSEELIL WSTSEFKFIE LSDGFCTGSS IMPQKKNPDV PELVRGKTGR
310 320 330 340 350 360
VYGNLMALLT VMKSLPLAYN KDMQEDKEPL FDTIDTVKGS LKIFADMIRE MRVNVATMRQ
370 380 390 400 410 420
AAAKGFSTAT DVADYLVRKG MPFRDAHEVV GKSVAYCIAE KKDLPELSIE EWRSFSDKID
430 440 450
EDIYDAITLE ASVNARRATG GTALERVKAE IERAKVGR