A5FS52

PR
Gene name
rsmA
Protein name
Ribosomal RNA small subunit methyltransferase A
Names
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase
Species
Dehalococcoides mccartyi (strain ATCC BAA-2100 / JCM 16839 / KCTC 5957 / BAV1)
KEGG Pathway
deb:DehaBAV1_0383
EC number
2.1.1.182: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5FS52

Entry ID Method Resolution Chain Position Source
AF-A5FS52-F1 Predicted AlphaFoldDB

No variants for A5FS52

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5FS52

No associated diseases with A5FS52

2 regional properties for A5FS52

Type Name Position InterPro Accession
conserved_site Ribosomal RNA adenine methylase transferase, conserved site 36 - 63 IPR020596
domain Ribosomal RNA adenine methylase transferase, N-terminal 20 - 191 IPR020598

Functions

Description
EC Number 2.1.1.182 Methyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA.
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGKDVPLLVA SAPSLMAQAK EMMEGYTLKA RKGLGQHFLI SQGVLNKILA AADLKPTDTV
70 80 90 100 110 120
IEVGPGLGVL TEELLKRAGQ VIAVEVDDKL IDALTEKFKG YPNFRLIHSD ILKTSPEEIL
130 140 150 160 170 180
GQNVPYKLVA NLPYYITSAV LRQFLEAKLK PESMVVMVQK EVAKNIVAKT GDMGLLTLSI
190 200 210 220 230 240
RFYGNPSLVS VVPGGAFYPP PEVDSAIVKI VIPQTTIMEG VSEVDFFKLA RAGFGTRRKT
250 260 270 280 290
LLNALAQGLG ISKPVILSLL NGAGIDPARR AETLSMEEWK KLCLEYAGNP C