A5FRZ3

PR
Gene name
aroA
Protein name
3-phosphoshikimate 1-carboxyvinyltransferase
Names
5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS
Species
Dehalococcoides mccartyi (strain ATCC BAA-2100 / JCM 16839 / KCTC 5957 / BAV1)
KEGG Pathway
deb:DehaBAV1_0440
EC number
2.5.1.19: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-84 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5FRZ3

Entry ID Method Resolution Chain Position Source
AF-A5FRZ3-F1 Predicted AlphaFoldDB

No variants for A5FRZ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5FRZ3

No associated diseases with A5FRZ3

2 regional properties for A5FRZ3

Type Name Position InterPro Accession
domain Enolpyruvate transferase domain 12 - 409 IPR001986
conserved_site 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site 328 - 346 IPR023193

Functions

Description
EC Number 2.5.1.19 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
3-phosphoshikimate 1-carboxyvinyltransferase activity Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.

3 GO annotations of biological process

Name Definition
aromatic amino acid family biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
chorismate biosynthetic process The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKIHLDKSLP GGNIAVPSSK SYTIRGLIAA AQANGQSHII SPLIADDTLA TRQVLSGLGI
70 80 90 100 110 120
NINTDTGSES WEITGNTFKA PSGNLFCRES AATLRFMSAV CARLPFECHL LAGHSLMRRP
130 140 150 160 170 180
MLPLIQALHQ LGIEIETRGN TTVINGQVIT RSKVSLPGNI SSQYVSALML MAPACTHGLE
190 200 210 220 230 240
IHLATPPASL PYLKMTKQTL GSFGIKVHSS IDWQEISIPP QPYLPARYRV EGDWSSASSF
250 260 270 280 290 300
LALGAIAAPV FISNLDTDSF QADRIMIKFL AEMGAEIESG QNWVKVNPKP LSGINADLTH
310 320 330 340 350 360
SIDLLPALAV AAACAKGQSI LSGVRQARIK ESNRIRAVSQ GLSAMGINII EEDDRLIIEG
370 380 390 400 410
GQPKGAEIDS FGDHRIAMAF GILGSVVGET HISDAECVTK TYPDFWKNLE SLGGKVTQDV