A5FQ74

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Dehalococcoides mccartyi (strain ATCC BAA-2100 / JCM 16839 / KCTC 5957 / BAV1)
KEGG Pathway
deb:DehaBAV1_1072
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

110-246 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5FQ74

Entry ID Method Resolution Chain Position Source
AF-A5FQ74-F1 Predicted AlphaFoldDB

No variants for A5FQ74

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5FQ74

No associated diseases with A5FQ74

3 regional properties for A5FQ74

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 274 - 283 IPR020557
domain Fumarate lyase, N-terminal 7 - 299 IPR022761
domain Argininosuccinate lyase, C-terminal 362 - 430 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSHIRSRFSK PADELVVRYT TSLPFDWRLY KEDIKCSTAH ARMLSKQGII STEDSQSIIN
70 80 90 100 110 120
GLNAILTEIE TGSFVFKPEM EDIHMAIEGR LFELIGEAAG RLHTARSRND QVATDVHLFV
130 140 150 160 170 180
KNACDKTINK IRTLQGTLLE QAEAHPQTAL PGYTHMQIAQ PVLLPHHLLA YFEMLERDCG
190 200 210 220 230 240
RFTDARKRAD VMPLGSGALA GVPYPLDREM VAKELGFSAI SQNSLDAVSE RDFILEYLSD
250 260 270 280 290 300
AAICQMHLSR LSEEMVIWSS AEYAFVELDD AYTTGSSIMP QKKNPDVAEL CRGKTGRVYG
310 320 330 340 350 360
SLNTMLTVMK GLPLSYNRDL QEDKEPLFDC VDTLGDSLEV FAGMIKTAKF KPERMLRALE
370 380 390 400 410 420
KGYVLATDIA DYLVGKGESF RNSHGIVARL VSYAVAQNKT FGELSLAEYR QFSNLFEKDI
430 440 450 460
YAVDIKSALN ARNLPGGTAP KQIAQAIARA KKILAEAGVK N