A5F4F5

PR
Gene name
plsB
Protein name
Glycerol-3-phosphate acyltransferase
Names
GPAT
Species
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
KEGG Pathway
vcr:VC395_0087
EC number
2.3.1.15: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

67-145 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5F4F5

Entry ID Method Resolution Chain Position Source
AF-A5F4F5-F1 Predicted AlphaFoldDB

No variants for A5F4F5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5F4F5

No associated diseases with A5F4F5

3 regional properties for A5F4F5

Type Name Position InterPro Accession
domain Phospholipid/glycerol acyltransferase 292 - 430 IPR002123
domain GPAT/DHAPAT, acyltransferase domain 282 - 483 IPR041728
domain GPAT/DHAPAT, C-terminal domain 438 - 776 IPR045520

Functions

Description
EC Number 2.3.1.15 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
glycerol-3-phosphate O-acyltransferase activity Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.
sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate.

1 GO annotations of biological process

Name Definition
CDP-diacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNSMSSGHLL SRSLLKLPMS VLVKGTAIPS NPIQDLDIDT HKPVIYALPF RSNVDLLTLQ
70 80 90 100 110 120
THAKEAGLPD PLEPLMLNGK AFQRYVFIAS RPTLLSSDQH VPSDSIALFS ELLTEHKLDS
130 140 150 160 170 180
ELDVQVIPAT VLWGRKPGKE GQERPYLQAL NGPEKALAVL ASGRDCLVRF SPVVSMRYMA
190 200 210 220 230 240
DTHGTDASIA HKLARVARIH FSRQKLAASG PNLPQRAQLF ARLMNSPAIE KAIADEAKSK
250 260 270 280 290 300
QIPLEKARKE AHDILDEIAA DFSYSLVKKG DRILGWLWNR IYQGLNINNA ATVRRLAQDG
310 320 330 340 350 360
HEIVYVPCHR SHMDYLLLSY VLYHEGMVPP HIAAGINLNF FPAGPIFRRG GAFFIRRSFK
370 380 390 400 410 420
GAPLYSTIFR EYLAELFAKG YSVEYFSEGG RSRTGRLLPA KTGMLAMTIQ AMLRGLNRPV
430 440 450 460 470 480
TLVPVYIGYE HVMEVGTYAK ELRGKRKEKE NAGLVLRTLR KLRNFGQGYV NFGEPIPLNQ
490 500 510 520 530 540
FLNETVPQWT QDIDPMGESK PQWMTPTVNK LATRMMTHIN DAAAVNAMTL CATALLASRQ
550 560 570 580 590 600
RALARDNLIK QVDCYLSLLR NVPYSATSTL PSESAEKLVE HAESLDKFVV ETDTMGDIIS
610 620 630 640 650 660
LDRNQSILMT YYRNNIIHLL ALPSLIAQLL IRQQSVSLEK VQATVAQIYP FLKQELFLRF
670 680 690 700 710 720
EAEELNDLVL RYVAELARQG LVTVEGKTVT LNQAQTQVLM LLGRIISETL QRYAIALNLL
730 740 750 760 770 780
VSCPHLGKAE LEEKSQEVAQ RLGRLHGINA PEFFDKGVFA SLFVTLQEQG YLDDQGRCVL
790 800 810
ETAKPLSRQL YALIYPEVRM TIQESLCQVD A