A5EV29

PR
Gene name
gpmA
Protein name
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Names
BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM
Species
Dichelobacter nodosus (strain VCS1703A)
KEGG Pathway
dno:DNO_0706
EC number
5.4.2.11: Phosphotransferases (phosphomutases)
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-70 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5EV29

Entry ID Method Resolution Chain Position Source
AF-A5EV29-F1 Predicted AlphaFoldDB

No variants for A5EV29

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5EV29

No associated diseases with A5EV29

1 regional properties for A5EV29

Type Name Position InterPro Accession
active_site Phosphoglycerate/bisphosphoglycerate mutase, active site 6 - 15 IPR001345

Functions

Description
EC Number 5.4.2.11 Phosphotransferases (phosphomutases)
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate.

2 GO annotations of biological process

Name Definition
gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKLVLVRHG QSQWNLENLF TGWTDVDLTE QGQKEAATAA QLLQKEGIFF QTAFTSYLKR
70 80 90 100 110 120
AIKTLNIILD VMDLDWIDVH KTWRLNEKHY GALQGLNKKE TAAQYGQEQV LLWRRSFDTA
130 140 150 160 170 180
PAALEYSDAR APHNDRRYQR VARQDLPLTE SLKDTIARIM PYWEVVIKPV LIAENTVLIV
190 200 210 220 230 240
AHGNSLRAII KHLKGISETE ITDLNLPTGI PYVFEFDDDM NLCADYFLGD TEAIKKLQES
VAKQSQ