A5EK14

PR
Gene name
queF
Protein name
NADPH-dependent 7-cyano-7-deazaguanine reductase
Names
7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase
Species
Bradyrhizobium sp (strain BTAi1 / ATCC BAA-1182)
KEGG Pathway
bbt:BBta_4472
EC number
1.7.1.13: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5EK14

Entry ID Method Resolution Chain Position Source
AF-A5EK14-F1 Predicted AlphaFoldDB

No variants for A5EK14

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5EK14

No associated diseases with A5EK14

No regional properties for A5EK14

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A5EK14

Functions

Description
EC Number 1.7.1.13 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
preQ1 synthase activity Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH.

1 GO annotations of biological process

Name Definition
queuosine biosynthetic process The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKRSIKSET SPELQLGRPV TAPDSPETAR LDRVPNPQKD TDYLARFTVP EFTSLCPVTG
70 80 90 100 110 120
QPDFAHLVID YAPGPWLVES KSLKLYLASF RNHGAFHEDC TVAIGKRLAT ELKPKWLRIG
130 140 150
GYWYPRGGIP IDVFWQTGKL PKGLWVPDQG VAPYRGRG