A5E8T8

PR
Gene name
tsaD
Protein name
tRNA N6-adenosine threonylcarbamoyltransferase
Names
N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Species
Bradyrhizobium sp (strain BTAi1 / ATCC BAA-1182)
KEGG Pathway
bbt:BBta_0289
EC number
2.3.1.234: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5E8T8

Entry ID Method Resolution Chain Position Source
AF-A5E8T8-F1 Predicted AlphaFoldDB

No variants for A5E8T8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5E8T8

No associated diseases with A5E8T8

2 regional properties for A5E8T8

Type Name Position InterPro Accession
domain Gcp-like domain 1 - 341 IPR000905
conserved_site Peptidase M22, conserved site 98 - 118 IPR017860

Functions

Description
EC Number 2.3.1.234 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
iron ion binding Binding to an iron (Fe) ion.
N(6)-L-threonylcarbamoyladenine synthase activity Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.

1 GO annotations of biological process

Name Definition
tRNA threonylcarbamoyladenosine modification The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGIETTCDE TAAAVVARDS DGKGRILSNV VRSQTDEHAL YGGVVPEIAA RAHVDMLDHL
70 80 90 100 110 120
IDAAMREAGI DYADLNGVAA AAGPGLIGGV IVGLTTAKAI ALVHDTPLIA VNHLEAHALT
130 140 150 160 170 180
PRLTDAIDFP YCLFLASGGH TQIVAVAGVG DYVRLGTTVD DAMGEAFDKV AKMLGLPYPG
190 200 210 220 230 240
GPQVEEAAQR GDAARFAFPR PMLGRSDANF SLSGLKTAVR NEIGRIAHVS AQDIADLCAS
250 260 270 280 290 300
FQAAVLESTA DRLRVGLDLF KQRFGAPTAL VAAGGVAANQ AIRAALDDVA QQAGTRLIMP
310 320 330 340 350
PPALCTDNGA MIAWAGLERL ALGMIDGMDA APRARWLLDA NASVPGKFAN TRAGF