A5E7S3

PR
Gene name
SEC23 (LELG_05662)
Protein name
Protein transport protein SEC23
Names
Species
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
KEGG Pathway
lel:LELG_05662
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

168-255 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5E7S3

Entry ID Method Resolution Chain Position Source
AF-A5E7S3-F1 Predicted AlphaFoldDB

No variants for A5E7S3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5E7S3

No associated diseases with A5E7S3

6 regional properties for A5E7S3

Type Name Position InterPro Accession
domain Zinc finger, Sec23/Sec24-type 53 - 92 IPR006895
domain Sec23/Sec24, trunk domain 121 - 393 IPR006896
domain Sec23/Sec24, helical domain 516 - 614 IPR006900
domain Gelsolin-like domain 629 - 716 IPR007123
domain Sec23/Sec24 beta-sandwich 404 - 502 IPR012990
domain Sec23, C-terminal 608 - 728 IPR037550

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
COPII vesicle coat One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

1 GO annotations of molecular function

Name Definition
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
COPII-coated vesicle budding The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNFEEAEDIN GVRFAWNAFP STKAEAGKIV VPTGALYTPL KQREDLPIAA YDPVYCSNQS
70 80 90 100 110 120
CKSILNPYCA VDPNGFWRCP LCQGRNSLPA HYHGINAENL PLELQNTSST VEYITARPVQ
130 140 150 160 170 180
NPPIFTFVID LCQDEENLKA LIEDVIVSFN YLPPNALVGL ITYGTMVQVH DLGSEKINKS
190 200 210 220 230 240
YIFRGDKEYT DKQISDMLNR PVAPVLNQQQ QQQQQQQPLQ QQQQLANSLT RFFLPLEDVE
250 260 270 280 290 300
FQLTSLLEGL NRDPWAVANG ARPLRSTGSA LNVAISLLGL TFPGFGARVM LFAAGPGTLN
310 320 330 340 350 360
PGLIVGNQLK EPIRSHSDID KDNAKHFKKA AKFYDALAAK AVKNCHTVDI FAGCYDQIGL
370 380 390 400 410 420
LEMKNLCNNT GGTMLLSDAF TTSIFKRSFL RLFNKDEEGY LLMGFNGTFE IRTSKELKVS
430 440 450 460 470 480
GLIGNASSLG VKTSNVSENE LGIGGSSHYR LCSTSPRHTY AVFFDVANTQ QLPPTAQSYI
490 500 510 520 530 540
QFITHYQHSS GTYRIRVTTV SNYLTSDEQS LTNSFDQEAA AVIMARVTIF KSEQDDGADV
550 560 570 580 590 600
LRWVDRMLIR LCQKFADYRK DQEESFRLGP QFQLYPQFIY YLRRSQFLQV FNNSPDETAF
610 620 630 640 650 660
YRHVLLTEDA NNSLIMIQPT LTSFTLDGEP EAVLLDSVSI KDDRILLLDT FFHILIFHGK
670 680 690 700 710 720
TISAWRKAKY QEQEEYANFK QLLDEPKQEA AELLADRYPL PRFIDTEEGG SQARFLYSKL
730 740 750 760
NPSVTYNTNE MIGGPGMGGA GGAIVLTDDV SLQVFMSHLQ KLVVSGSS