A5E6W6

PR
Gene name
RRP3
Protein name
ATP-dependent rRNA helicase RRP3
Names
Species
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
KEGG Pathway
lel:LELG_05355
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-125 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5E6W6

Entry ID Method Resolution Chain Position Source
AF-A5E6W6-F1 Predicted AlphaFoldDB

No variants for A5E6W6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5E6W6

No associated diseases with A5E6W6

4 regional properties for A5E6W6

Type Name Position InterPro Accession
domain Helicase, C-terminal 326 - 471 IPR001650
domain DEAD/DEAH box helicase domain 122 - 289 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 117 - 315 IPR014001
domain RNA helicase, DEAD-box type, Q motif 98 - 126 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSKGIQKKT KAVDATKKLA EKIKKQALKQ KALASASSAA STKESLPVSE TISISTSETP
70 80 90 100 110 120
VSDVSELSNK EDLSTKKDQS SASSSSSTSS SSSPPSVQSF TEFDLVPELL ESIQSLKYTQ
130 140 150 160 170 180
PTPIQAAAIP HALQGKDIVG IAETGSGKTA AFAIPILQTL YTAAQPYYAL VLAPTRELAF
190 200 210 220 230 240
QIKETFDALG SSMGLRSVCI IGGMSMMEQA RDLMRKPHVI IATPGRLIDH LEHTKGFSLK
250 260 270 280 290 300
KLQYLVMDEV DRMIDLDYAK AIDQILKQIP SHQRITYLYT ATMSREIEKF KRSLNSPVQV
310 320 330 340 350 360
EIVKLEKVPD KLKQTMCLTS PNTKDTRLIQ IVNLDSMKRV IIFTRTVVHT RRCCLMLLNL
370 380 390 400 410 420
GFKCVELHGQ MPQSRRLGAI NKFKAGTPIL VATDVAARGL DIPAVDLVIN YDIPDPTLYI
430 440 450 460 470 480
HRVGRTARAG KAGKAISLVT QYDLESYLRI ENTLGTKLPK EDLPLDEMQG LQVSVDRALS
490 500
KAIQMLRNEE NDNKLRHRGR SNNK