A5DTK7

PR
Gene name
MSS116 (LELG_00693)
Protein name
ATP-dependent RNA helicase MSS116, mitochondrial
Names
Species
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
KEGG Pathway
lel:LELG_00693
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

560-692 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5DTK7

Entry ID Method Resolution Chain Position Source
AF-A5DTK7-F1 Predicted AlphaFoldDB

No variants for A5DTK7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5DTK7

No associated diseases with A5DTK7

3 regional properties for A5DTK7

Type Name Position InterPro Accession
domain NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal 71 - 121 IPR001516
domain NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit 137 - 418 IPR001750
domain NADH dehydrogenase subunit 5, C-terminal 425 - 604 IPR010934

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

3 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
regulation of translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMIARFGKQV LRKNVLVSNR IHFPVISRGF HNSFINKSDD LKSPPIDITK GQTEAKVETK
70 80 90 100 110 120
KDKFAGFGLD LDELIGETAK GSQVTEQTEL TKSEEEEKKK KNINTNTNKN DRKSVPAISL
130 140 150 160 170 180
EDFNPSQFKD FKNTGLIDDV ILRALDRAHF KDLTPIQQKS IVPLLETERG MVCRAKTGTG
190 200 210 220 230 240
KTLTFLIPTL QSAVSRKIAS GGRSSGVDTV IIVPTRDLAL QIYDEYQKVL RGISGSRKPH
250 260 270 280 290 300
ISYVIGGMKN SFNPRNPSEI VIATPGRLEA DLRSPLFASA FTDIKYRVYD EADRLLDVGF
310 320 330 340 350 360
EPTLDSIDRS IKMIRSDDAE PLKSLLFSAT VDARLDQFAK QHINKKYDYI NTVPEDDPEV
370 380 390 400 410 420
HENIHQVMYK CKDAIDKFGS FFNYVNQLVK DSPDMKMMVF LPTQTAVEFL YSYMSEACHK
430 440 450 460 470 480
HDVDIDIFHL HGKRSASQRQ RALSNFKRDD SGILITTDVA ARGIDVKGVT HVVQLFPSSE
490 500 510 520 530 540
IADYVHKVGR TGRAGKEGKA VLFITQPEMA YVRRLNSERG VTFEQVHESS EIDNSIDFFE
550 560 570 580 590 600
GMRPDEQVAN DFFYTLMSFL AQISSTYRLR ADDLVAENVS LYRAILQKPD AKLSLRAASA
610 620 630 640 650 660
LIKRLNRDVV REFFEQGRGG NNGGYGGYGG YGGSSYGRSG GSNRYSGGGG NRSEKRFSFA
670 680 690
GRGGNSGGHS GRGRGGRSGY SGGRSSQYSD WE