Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A5DEX5

Entry ID Method Resolution Chain Position Source
AF-A5DEX5-F1 Predicted AlphaFoldDB

No variants for A5DEX5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5DEX5

No associated diseases with A5DEX5

2 regional properties for A5DEX5

Type Name Position InterPro Accession
conserved_site Argininosuccinate synthase, conserved site 10 - 18 IPR018223-1
conserved_site Argininosuccinate synthase, conserved site 117 - 128 IPR018223-2

Functions

Description
EC Number
Subcellular Localization
  • Preautophagosomal structure membrane ; Multi-pass membrane protein
  • Cytoplasmic vesicle membrane ; Multi-pass membrane protein
  • Golgi apparatus membrane ; Multi-pass membrane protein
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytoplasmic vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPDVHLSSSF AEGNTSEQNE NDTFLSRIFG FHSIYNQLDN YQYYDPESQV GDSMIRRDGG
70 80 90 100 110 120
SNHLLDSESD SDLSSIESSS SSQDQPPSIH ANDIQMQPYE PPTQPYGEID PQPQNAPIMT
130 140 150 160 170 180
ESAPSHGILN NGAVSTDEAQ VQFRKTKTLP SFHTMYQRQA RGRVFIPSRE RALYLWANIV
190 200 210 220 230 240
NMDEFLSDLY YYYRGRGVMN IVLGRIVDLA TLVFVIGFAS FLAWGVDYDK FLSRGQKSLT
250 260 270 280 290 300
LSDLIIPHYI SKAPAMAKLL LFGFAIYITL RIVQLYFDFR YKLSEIRNFY RQLLDIPHDD
310 320 330 340 350 360
ELMTISWATI VERLMELKDF NTLTSSSHYV NDLKSKVRLN AHDIANRIMR KENYIIALIN
370 380 390 400 410 420
KDTLNLGFEI PLLSVLNPIL NTRAVLTRTL EWNLKLCIYN FVFNNQGQVN PNVLKDYNRN
430 440 450 460 470 480
MLAKELSSRF KMAAIINLLL CPFIVVYFVL LYFFRYFNEY KTNPSSLIGL RQYTPWAEWK
490 500 510 520 530 540
LREFNELPHF FVKRLQLSIG PANTYINQFP RGFLVVNIMT LVNFVAGAIT AVLVVMGLWF
550 560 570 580 590 600
EDEEHSFWAF ELTENKSALF YISIFGTIWA VTAGSLATDT SSTESANSSS PFYYDPEASL
610 620 630 640 650 660
RYVTQFTHYM PSTWSKKLHT AEVKGEFCEL FSLKIVVIIN ELLSLVLTPF ILWFKLSSQS
670 680 690 700 710 720
GAIIDFVREY SVYVDGLGYV CYFAMFNFEK KDKNMMHDLN KKKKKSPSHR TKRDDIEEEE
730 740 750 760 770 780
ESDNGVPNGD DKMIKSYMYF LESYDDRERA ARPTPKSRQL PRTRLPPGSI SESTYNVDHI
790 800
LEEEELPQGK SAGVFGMINQ FYKQDLGR