A5DCP8
Gene name |
PAN3 |
Protein name |
PAN2-PAN3 deadenylation complex subunit PAN3 |
Names |
PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3 |
Species |
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii) |
KEGG Pathway |
pgu:PGUG_01053 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A5DCP8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A5DCP8-F1 | Predicted | AlphaFoldDB |
No variants for A5DCP8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A5DCP8 | |||||
No associated diseases with A5DCP8
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| PAN complex | A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| metal ion binding | Binding to a metal ion. |
| protein kinase activity | Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
| nuclear-transcribed mRNA poly(A) tail shortening | Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. |
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNINLDSAKG | TLCKNILIYG | YCKYENKGCA | FSHRRNNNAN | SGPGATPAKS | VATTPTSDKR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KFNVNTPSFQ | PSTAPVQGLA | NKFAGLSPKV | KDIPVFVPSG | TPASPAQSTP | STGNQEQPMP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TSTVSNVPER | KFNTSTPSFT | PSQPIPAPPP | QNTSSPPTNP | YLMNQPGPPT | DMYYQSAYPL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QYHLYAPAPP | PRLAITHSSH | QVDAHSLFID | SELRETLQKR | NEATLQSYPG | GPEIVDVYHT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VVPIAAEGVS | KIWKVSSSVY | KGVSNVDGNV | YALRKIEDFK | IINETPFRTI | KRWHGLQSAN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IVKIQDAFTT | VAFGSPSLVV | AYDYYPNAST | LLEQHVNRRL | GGRLEPLTED | ILWLYLTQLV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NAVRTVHKKK | LAARSSLDLS | KIIVTTNRIR | LAAIGMSDIL | NWEADDAEIA | RVGLPTYMEN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LQQEDIRNMA | RLMVDLTTVM | NPVVQNDIFK | LKSSGLSTDF | VAAVQDLSNT | DDLESYIRKH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LAIRLLDVVD | MLEDSNDYLE | SQLSTELENA | RLVRLMTKIN | FIVDRPEWDN | EATAAAAGWT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ENGPKYLLKL | FRDFVFFQTD | EMGKPVTDLS | RVLVTLNKLD | AGIDEKFLLV | SRDEKTCIVV |
| 610 | |||||
| SYKEIRDLLE | SVFRTITRGK |