A5DC85

PR
Gene name
DBP9 (PGUG_00890)
Protein name
ATP-dependent RNA helicase DBP9
Names
Species
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
KEGG Pathway
pgu:PGUG_00890
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-121 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5DC85

Entry ID Method Resolution Chain Position Source
AF-A5DC85-F1 Predicted AlphaFoldDB

No variants for A5DC85

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5DC85

No associated diseases with A5DC85

4 regional properties for A5DC85

Type Name Position InterPro Accession
domain Helicase, C-terminal 269 - 467 IPR001650
domain DEAD/DEAH box helicase domain 59 - 234 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 54 - 260 IPR014001
domain RNA helicase, DEAD-box type, Q motif 35 - 63 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQYHLQVEPH RCAHRTFPSP MTDAVVASEY LDESAKWENF KLDPRLLQAV YQLGFEKPTL
70 80 90 100 110 120
IQSNAIPLSL EDKRDIIAKA STGSGKTGAY SIPIIQNILS EGLSEHNIKS VILVPTKELA
130 140 150 160 170 180
NQVTKFIEKL LVYCNSITQI NLATNVSDQV VVSLLSAKPE IIISTPSRLT TVLEKHASIV
190 200 210 220 230 240
DLTTVTSLAI DEVDLMLSYG YMEDLQKLDD FLPIKRNLQT YLMSATVNDD VNDLKARFCT
250 260 270 280 290 300
KPAIIKLNDN EENQNRLVQF YARTSEFDKF LFAYVIFKLH LIKGKTLAFV NNIDRGYRLK
310 320 330 340 350 360
LFLEQFGVRC CILNSELPVN SRLHIVDEFN KNVYNLLIAS DESTEVTEQE GEDDQEDSKP
370 380 390 400 410 420
EKSKKKKGKK VDGEYGVSRG VDFRNVACVL NFDLPTTSRS YVHRVGRTAR AGKAGMALSF
430 440 450 460 470 480
VVPVKEVGKH KTATNPGAKR DEKVLARIVK SQSKNGFEIK PYQFDMTQVE GFRYRAEDAF
490 500 510 520 530 540
RAVTSAAIRE ARIRELKNEI MNSEKLKRFF EENPQDLASL RHDKELHPAK VQSQLKRVPD
550 560 570 580
YLLPESARQD PKKIGFVPFH KNKVHKNRKR KGGKKVDALK SFRQKK