A5DC23
Gene name |
TRM8 |
Protein name |
tRNA (guanine-N(7)-)-methyltransferase |
Names |
Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase |
Species |
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii) |
KEGG Pathway |
pgu:PGUG_00828 |
EC number |
2.1.1.33: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A5DC23
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A5DC23-F1 | Predicted | AlphaFoldDB |
No variants for A5DC23
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A5DC23 | |||||
No associated diseases with A5DC23
No regional properties for A5DC23
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A5DC23 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.33 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA (guanine-N7-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine. |
| tRNA binding | Binding to a transfer RNA. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTDSESKRR | AYREEKEGAR | KKSVKLAPEA | TPESKPDLPR | KRYYRQRAHS | NPFSDHSLDY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PRNPDAMEWG | KLYPEYANTD | KKVEIADIGC | GYGGLMIGLA | KEYPQTMILG | MEIRVQVTQY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VEDRIIALRE | KHEKDEVNYQ | NIAVLRGNAM | KFLPNFFHRG | QLKKMFFCFP | DPHFKQRKHK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ARIITTTLLS | EYAYVLREEG | VLYTITDVED | LHIWMVKHLD | DHPLFERLDK | EWEKNDKCVS |
| 250 | 260 | 270 | |||
| IMYGSTEEGQ | KVARNKGSKF | VACFRRVANP | EE |