A5CYJ1

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)
KEGG Pathway
pth:PTH_2753
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

489-615 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5CYJ1

Entry ID Method Resolution Chain Position Source
AF-A5CYJ1-F1 Predicted AlphaFoldDB

No variants for A5CYJ1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5CYJ1

No associated diseases with A5CYJ1

8 regional properties for A5CYJ1

Type Name Position InterPro Accession
conserved_site SEC-C motif 864 - 882 IPR004027
domain SecA DEAD-like, N-terminal 5 - 382 IPR011115
domain SecA Wing/Scaffold 618 - 829 IPR011116
domain SecA, preprotein cross-linking domain 226 - 338 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 87 - 245 IPR014001
domain SecA motor DEAD 1 - 620 IPR014018
conserved_site SecA conserved site 480 - 495 IPR020937
domain SecA, C-terminal helicase domain 400 - 590 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGFIKDWLD DNAREIKKLQ RVVDEINKLE PEIAAKSDGD LQGMTAVFRD RLDRGESLDG
70 80 90 100 110 120
ILPEAFAVVR EASRRVLGMR HFDVQLMGGI VLHQGRIAEM KTGEGKTLVA TLPVYLNALT
130 140 150 160 170 180
GKGVHVVTVN DYLARRDSEW MGQVYKYLGL SVGLIVHGLD WEERKRSYRA DVTYGTNNEF
190 200 210 220 230 240
GFDYLRDNMA LHPDQLVQRE LNYAIVDEVD SILIDEARTP LIISGQAEKS TDLYYTFARI
250 260 270 280 290 300
VPRLVPEVDY NVDEKAHTVV ITETGVAKVE KMLGVENLYD DRNIELTHHL NQALKAHALM
310 320 330 340 350 360
KRDRDYVVKD GQVIIVDEFT GRLMFGRRYS DGLHQAIEAK EGVKIERESQ TLATITFQNY
370 380 390 400 410 420
FRMYRKLAGM TGTAATEEQE FKKIYGLDVV VIPTNKPMIR KDLPDVIYKT EQAKFRAVVE
430 440 450 460 470 480
EIAARHARGQ PVLVGTISIE KSEMLSGMLK KRGIPHQVLN AKYHDKEAEI VAQAGRLGAV
490 500 510 520 530 540
TIATNMAGRG TDILLGGNPE FLARNELRRM GHECEAAAEI AGAPAEQDGA YKALLEKFRR
550 560 570 580 590 600
QTEEERRRVV ELGGLHIIGT ERHESRRIDN QLRGRCGRQG DPGSSQFFSS LEDDLMRLFG
610 620 630 640 650 660
SENIAGIMDR LGIDEDMPIE HAMITKSIEA AQKRVENRNF DIRKHVLQYD DVMNQQRELI
670 680 690 700 710 720
YRQRRQVLTG ENLKENVLEM IGTCVERAVN TYAPEGVHPE EWDLKGLLEH AEHLFLPGHG
730 740 750 760 770 780
LTAGDLAGMS RRELQEFLTE RSRAAYDARE QELGADTMRE IERVIMLRIV DEKWMDHLDA
790 800 810 820 830 840
MDQLREGIGL RAYGQKDPLV EYKFEGYEMF QNMIASIQDD VVRYIFRVNV VQPQQQRQSR
850 860 870 880
RVVENRYAEE GPKQPARREN KVGRNDPCPC GSGRKYKKCC GRAEAV