Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A5CXX6

Entry ID Method Resolution Chain Position Source
AF-A5CXX6-F1 Predicted AlphaFoldDB

No variants for A5CXX6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5CXX6

No associated diseases with A5CXX6

5 regional properties for A5CXX6

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 315 - 482 IPR000795
domain Small GTP-binding protein domain 319 - 474 IPR005225
domain Translation initiation factor IF-2, N-terminal 241 - 290 IPR006847
domain Translation initiation factor IF- 2, domain 3 591 - 705 IPR023115
domain Translation initiation factor IF-2, domain II 490 - 584 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAHTVQTLSK LLKKTPDEVV TILANAGVDG KNSDSVISAE ERKILMSSLS KRPIRRSSMS
70 80 90 100 110 120
VFRKAGTKSN AVSVSDVKVK VRSKRLTQPI TMIDEQSKVV ANEMARAALA ALDAGRNADE
130 140 150 160 170 180
ILLAQDARRL EMVRLQKAQV EVVEIQKETV KKVQEKEAEK KVEKLKTADK PKEGNKPKRL
190 200 210 220 230 240
RNTSSDNNTR KQLHVARHNP NRRLKKKDRT HLSQKIQAEQ AQHAFQKPIE KVIHEVAIVG
250 260 270 280 290 300
NIKVTELAQK MATKAGEVLK VLMGMGVMVT LNDVIDQDTA LLVVEEMGHK GIISVEETIE
310 320 330 340 350 360
DVLIEQLKYN EHESARPPIV TIMGHVDHGK TSLLDYIRQA KVAHGEVGGI TQHIGAYQVQ
370 380 390 400 410 420
SNGNIITFID TPGHAAFSKM RFRGANVTDI VILVVAADDG VMPQTIESIK HTQIVGVPMI
430 440 450 460 470 480
VAINKIDKEG TDVDKIKQVL STYDVISEDW GGDVIMVPVS AHTGEGVDAL LDAISLTAEI
490 500 510 520 530 540
LEFSAVSEGP AHGTVLEARL EKGRGKVTTI LVQSGTLNKG DIMIAGFEYG KVKQIVDDKG
550 560 570 580 590 600
KILKLAMPSM PVEVLGLSGV PNSGDEVIVV GSERKAREVA DFRKSKDREV QLQKQQASKM
610 620 630 640 650 660
ENFLMKMEKG DISTVNVLLK ADVRGSAQAL IEALEELSTD EVRVKVVSSG VGGINNTDIT
670 680 690 700 710 720
LAATSSALVL GFNVRADAVA RKTADNEGVR VEYYSIIYNL INDVKAIMSG LLSPELSENI
730 740 750 760 770 780
IGIASVKNIF KSQKMGDIAG CMVDEGMVKR DSLIRVLRDS VVIFDGKLES LRRFKDDVNE
790 800 810
VKSGTECGIG VLNYTDVQPG DQIEIFERVE RARIL