A4YVC1
Gene name |
queF |
Protein name |
NADPH-dependent 7-cyano-7-deazaguanine reductase |
Names |
7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase |
Species |
Bradyrhizobium sp (strain ORS 278) |
KEGG Pathway |
bra:BRADO4095 |
EC number |
1.7.1.13: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A4YVC1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A4YVC1-F1 | Predicted | AlphaFoldDB |
No variants for A4YVC1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A4YVC1 | |||||
No associated diseases with A4YVC1
No regional properties for A4YVC1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A4YVC1 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 1.7.1.13 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| preQ1 synthase activity | Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| queuosine biosynthetic process | The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKRSNTTMT | SAGLQLGREV | APPDSPETAK | LDRVPNPQRD | TDYLARFTVP | EFTSLCPVTG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QPDFAHLVID | YAPGPWLVES | KSLKLYLASF | RNHGAFHEDC | TVAIGKRLTA | EIKPKWLRIG |
| 130 | 140 | 150 | |||
| GYWYPRGGIP | IDVFWQTGRL | PKGLWVPDQG | VAPYRGRG |