A4YCR0

PR
Gene name
rpo1C
Protein name
DNA-directed RNA polymerase subunit Rpo1C
Names
DNA-directed RNA polymerase subunit A''
Species
Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
KEGG Pathway
mse:Msed_0035
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-59 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4YCR0

Entry ID Method Resolution Chain Position Source
AF-A4YCR0-F1 Predicted AlphaFoldDB

No variants for A4YCR0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4YCR0

No associated diseases with A4YCR0

1 regional properties for A4YCR0

Type Name Position InterPro Accession
domain RNA polymerase Rpb1, domain 5 42 - 338 IPR007081

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MINNTDNEYL EQKLSELSKK VPASIISKLR ESITNSPIEI TRDEIDKIIE IVMKDYLSSL
70 80 90 100 110 120
VHPGEAIGVV AAQSIGEPGT QMTLRTFHFA GVRELNVTLG LPRLIEIVDA RKVPSTPMMT
130 140 150 160 170 180
IYLNEEYAKD RDMALEVARR IEYTRVEHVV ETVNLDVGGM GIILKLDPVL LKDKGLSTED
190 200 210 220 230 240
VEKVIKKLKM GDYRVENSDE YTIAIYFENM ETVTGLFKAR EKILSTKIKG VKGIKRAIIR
250 260 270 280 290 300
KKGDEYVIIT DGSNLEGVLG VKGVDVSRIE TNNLHEVESV LGVEAARELI TREIKRVLEE
310 320 330 340 350 360
QGLDVDIRHI ELVSDIMTRT GEVRQIGRHG VTGEKTSVLA RAAFEVTVKH LLDAAARGDM
370 380 390
EEFKGVVENI IIGQPIKLGT GMVELLMRPA NR