A4XWU3

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Pseudomonas mendocina (strain ymp)
KEGG Pathway
pmy:Pmen_3055
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

134-240 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4XWU3

Entry ID Method Resolution Chain Position Source
AF-A4XWU3-F1 Predicted AlphaFoldDB

No variants for A4XWU3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4XWU3

No associated diseases with A4XWU3

6 regional properties for A4XWU3

Type Name Position InterPro Accession
domain ACT domain 706 - 784 IPR002912-1
domain ACT domain 815 - 897 IPR002912-2
domain Polymerase, nucleotidyl transferase domain 67 - 117 IPR002934
domain HD/PDEase domain 457 - 611 IPR003607
domain HD domain 461 - 583 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 185 - 321 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPQMDPELFD RGQFQAELAL KSSPIAAFKK AIRHAREVLD ARFKGGRDIR RLVEDRAWFV
70 80 90 100 110 120
DQILQEAWKR FAWSEDADIA LLAVGGYGRG ELHPYSDIDL LILLDSSDHE IFREPIEGFL
130 140 150 160 170 180
TLLWDIGLEV GQSVRSVDEC AEEARADLTV ITNLMESRTI AGPEHLRQRM QQVTSSEQMW
190 200 210 220 230 240
PSKHFYLAKR EERKARHAKY NDTEYNLEPN VKGSPGGLRD IQTVLWVARR QFGTLNLQAL
250 260 270 280 290 300
VGQGFLLESE YALLSSSQEF LWKVRYALHM LAGRAEDRLL FDYQARIAAL FGYQDGDGKR
310 320 330 340 350 360
SIEHFMQKYY RVVMGISELS DLINQHFEEV ILRAGESGPA TPLNSRFQVR DGYIEVTHPN
370 380 390 400 410 420
VFKRTPFAIL EVFVLMAQNP EIKGVRADSI RLLRDSRHLI DDDFRKDIRN TSLFIELFKC
430 440 450 460 470 480
KEGIHRNLRR MNRYGILGRY LPEFGHIVGQ MQHDLFHIYT VDAHTLNLIK HLRKFRWPEL
490 500 510 520 530 540
AEKFPLASKL IDRLPKPELI YLAGLYHDIG KGRGGDHSEL GAVDAEAFAR RHQLPAWDSA
550 560 570 580 590 600
LIVWLVQHHL VMSTTAQRKD LSDPQVIHDF AQFVGDQTHL DYLYVLTVAD INATNPSLWN
610 620 630 640 650 660
SWRASLLRQL YTETKRALRR GLENPLDREE QIRQTQSAAL DILVRGGTDP DDAEQLWSQL
670 680 690 700 710 720
GDDYFLRHTA NDVAWHTEAI LQHPADSGPL VLIKETTQRE FEGGTQIFIY APDQHDFFAV
730 740 750 760 770 780
TVAAMSQLNL NIHDARIITS TSQFTLDTYV VLDADGGSIG DNPARIKQIR EGLIEALKNP
790 800 810 820 830 840
DEYPTIIQRR VPRQLKHFAF APQVTIHNDA QRPVTILELT APDRPGLLAR IGRIFLEYDL
850 860 870 880 890
SLQNAKIATL GERVEDVFFV TDANNQPLSD PELCARLQET IVRRLSEPSA QPQSLQIDI