A4XV57

PR
Gene name
gpsA
Protein name
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Names
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
Species
Pseudomonas mendocina (strain ymp)
KEGG Pathway
pmy:Pmen_2467
EC number
1.1.1.94: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

6-128 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4XV57

Entry ID Method Resolution Chain Position Source
AF-A4XV57-F1 Predicted AlphaFoldDB

No variants for A4XV57

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4XV57

No associated diseases with A4XV57

5 regional properties for A4XV57

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 223 - 349 IPR005225
domain GTP binding domain 225 - 341 IPR006073
domain GTP-binding protein TrmE, N-terminal 11 - 126 IPR018948
domain MnmE, helical domain 129 - 453 IPR025867
domain TrmE-type guanine nucleotide-binding domain 221 - 380 IPR031168

Functions

Description
EC Number 1.1.1.94 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
glycerol-3-phosphate dehydrogenase complex An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.

2 GO annotations of molecular function

Name Definition
glycerol-3-phosphate dehydrogenase [NAD+] activity Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.

5 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
glycerol-3-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.
glycerol-3-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.
glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTELQPIAVL GGGSFGTALA NLLAENGQRV LQWMRDPEQA GQMRRSGENP RYLKGVKLHP
70 80 90 100 110 120
GIEPTSDLGA ALQQAELVFV ALPSSALRDA LQPVAAQLSG KMLVSTTKGI EARTFKLMSE
130 140 150 160 170 180
ILEEIAPDAR IGVLSGPNLA KEVADHALTA TVIASEDEEL CLRVQQALHG RTFRVYASAD
190 200 210 220 230 240
RFGVELGGAL KNVYAIMSGM AAALGMGENT KSMLITRALA EMTRFAVKLG ANPMTFLGLA
250 260 270 280 290 300
GVGDLIVTCS SPKSRNYQVG FALGEGLSLD EAVQRLGEVA EGVNTLKVLK ARAEELEVYM
310 320 330
PLVAGLHAVL FEGRTLAQVI ELLMRGEPKT DVDFIPTAGF