Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A4XSC5

Entry ID Method Resolution Chain Position Source
AF-A4XSC5-F1 Predicted AlphaFoldDB

No variants for A4XSC5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4XSC5

No associated diseases with A4XSC5

4 regional properties for A4XSC5

Type Name Position InterPro Accession
domain K Homology domain, type 2 199 - 285 IPR004044
domain Small GTP-binding protein domain 9 - 170 IPR005225
domain GTP binding domain 12 - 126 IPR006073
domain Era-type guanine nucleotide-binding (G) domain 8 - 176 IPR030388

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cell inner membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
small ribosomal subunit rRNA binding Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.

1 GO annotations of biological process

Name Definition
ribosomal small subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDAPVSRCG YVAIVGRPNV GKSTLLNHIL GQKLAITSRK PQTTRHNMLG IKTEGEIQAV
70 80 90 100 110 120
YVDTPGLHKH NDKALNRYMN RSASSALKDV DVVVFVVDRT RWTDEDQLVL EKVQHVKCPI
130 140 150 160 170 180
LLAVNKADRL EDKSELLPHL NWLAEQLPQA EIVPISALQG QNLDTLEKLV GERLPESEHF
190 200 210 220 230 240
YPEDQITDRS SRFLAAELIR EKIMRQLGAE LPYQITVEIE EFKQDGPILH IHGLILVERD
250 260 270 280 290
GQKKIIIGDK GERIKRIGQD ARKDMETMFD SKVMLNLWVK VKGGWSDDER ALRSLGYLD