A4XN50
Gene name |
mnmG |
Protein name |
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG |
Names |
Glucose-inhibited division protein A |
Species |
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331) |
KEGG Pathway |
csc:Csac_2770 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A4XN50
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A4XN50-F1 | Predicted | AlphaFoldDB |
No variants for A4XN50
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A4XN50 | |||||
No associated diseases with A4XN50
5 regional properties for A4XN50
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | MnmG-related, conserved site | 276 - 290 | IPR020595-1 |
| conserved_site | MnmG-related, conserved site | 371 - 394 | IPR020595-2 |
| domain | tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal | 404 - 619 | IPR026904 |
| domain | MnmG, N-terminal domain | 10 - 401 | IPR040131 |
| domain | tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain | 549 - 620 | IPR047001 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| flavin adenine dinucleotide binding | Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA wobble uridine modification | The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEFVAGEYDI | VVVGAGHAGC | EAALACARLG | LKTIVFAINL | DSIGNMPCNP | SIGGTGKGHL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VREIDALGGE | MGKAADATAI | QVRILNRAKG | PAVYSLRAQC | DRARYKLYMK | RVLESQPNLD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IRQGEVCDIL | VEDGKVTGVK | LTTGAIFRAK | AVVLATGTFL | GGRIIIGETV | YDGGPDGMHP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AKYLTESLKK | LGIEMMRFKT | GTPARVHRRS | LDFSKMQIQL | GDEVITPFSF | EHETLEIEQV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PCYLTYTTEE | THRIIRENLH | RAPLFTGLIQ | GVGPRYCPSI | EDKVVRFADK | PRHQVFIEPM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GRDTEEMYVQ | GMSSSLPEDV | QIKMYRSVIG | LENVQIMRPA | YAIEYDCINP | LQLEATLQFK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KIKGLFSAGQ | INGTSGYEEA | AAQGIIAGIN | AAMYVKGKEM | LVLDRSQAYI | GVLIDDLVTK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GTNEPYRIMT | SRAEYRLILR | QDNADLRLTE | IGYRIGLISQ | ERYEKFLKKK | KMIEDEIERL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KKTVIAPSDK | VNKFLIEHGS | SPISTGVKLS | ELLKRPELSY | EALREIDPQR | PDLPRSVKEE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VEIEIKYEGY | IKKQLQQIEQ | FKKLENKKIP | EWVDYNQISG | LSTEAKQKLS | QIRPASIGQA |
| 610 | 620 | ||||
| SRISGVSPAD | ISVLLIWLEQ | AKKGSK |