Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A4XLD4

Entry ID Method Resolution Chain Position Source
AF-A4XLD4-F1 Predicted AlphaFoldDB

No variants for A4XLD4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4XLD4

No associated diseases with A4XLD4

6 regional properties for A4XLD4

Type Name Position InterPro Accession
domain HD/PDEase domain 336 - 452 IPR003607
domain K Homology domain 212 - 279 IPR004087
domain K Homology domain, type 1 218 - 271 IPR004088
domain HD domain 340 - 433 IPR006674
domain HDIG domain 336 - 413 IPR006675
domain Ribonuclease Y, N-terminal 17 - 209 IPR022711

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQKISDTLKL IITAGVSIAL AIVAFFLGYL YRKKIAEKTI KSAEQEAQRI VEEAKKQAEA
70 80 90 100 110 120
YKKEATLLAK EEIHRARSEF DREVRERRAE LQRFERRLIQ KEEMLDKKMA AVEEKEEQLN
130 140 150 160 170 180
QKIKDVQKLQ EEIELLKQKQ QEELQRISGL TQEEARQIIL KSVEQDVKHD VALMIKELEQ
190 200 210 220 230 240
QAKEEADKKA REIIALAIQR YSSDYVAENT VSVVTLPNDE MKGRIIGREG RNIKTFETVT
250 260 270 280 290 300
GIDLIIDDTP EAVILSGFDP IRREIAKLTL EKLILDGRIH PARIEEMYEK AKREVENKIR
310 320 330 340 350 360
EEGERVVFEL GIHNLHPELI KLIGKLRYRT SYGQNVLAHS IEVANIAGIM AAELGLDQSI
370 380 390 400 410 420
AKRAGLLHDI GKAVDHEVEG SHALIGYDLA KRYKETNPDV LEAIGGHHGE METRSIYNVL
430 440 450 460 470 480
IQAADSVSAA RPGARRESLE SYIKRLQKLE EIANSFDGVE KAYAIQAGRE IRIMVKPDHV
490 500 510 520
SDDDIVIMAR EIVKRIESEL DYPGQIKVNV IREVRAVEYA K