A4X3K6
Gene name |
prfB |
Protein name |
Peptide chain release factor 2 |
Names |
RF-2 |
Species |
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) |
KEGG Pathway |
stp:Strop_0981 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A4X3K6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A4X3K6-F1 | Predicted | AlphaFoldDB |
No variants for A4X3K6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A4X3K6 | |||||
No associated diseases with A4X3K6
4 regional properties for A4X3K6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Biotin/lipoyl attachment | 1 - 69 | IPR000089 |
| domain | 2-oxoacid dehydrogenase acyltransferase, catalytic domain | 178 - 409 | IPR001078 |
| binding_site | 2-oxo acid dehydrogenase, lipoyl-binding site | 19 - 48 | IPR003016 |
| domain | Peripheral subunit-binding domain | 112 - 150 | IPR004167 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| translation release factor activity, codon specific | A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTDADYAEQL | KDLDATLRNI | ESVLDIDRLR | ADKARLEEAA | SAPDLWDDQA | RAQQVTSQLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YVNGEINKLA | ELRSRLDDAK | VLLELAEAES | DPGALTEVEA | EVAGLAKAID | EMEVRTLLSG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EYDSREALVA | IRAGAGGVDA | ADFAEMLLRM | YLRWAERHGY | PTEVYETSYA | EEAGLKSATF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TVKVPYAYGT | LSVESGTHRL | VRISPFDNQG | RRQTSFAGVE | VLPVVEQTDH | IDIPENEMRF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DVYRSSGPGG | QSVNTTDSAV | RITHIPTGIV | VTCQNEKSQL | QNKASALRVL | QARLLERKRQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EEQAKLQGLK | TDAAGSWGDQ | MRSYVLHPYQ | MVKDLRTEQE | TGTPAAVFDG | ELDAFIEAGI |
| 370 | |||||
| RWRKQQQLAD | DNA |