Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A4VPP0

Entry ID Method Resolution Chain Position Source
AF-A4VPP0-F1 Predicted AlphaFoldDB

No variants for A4VPP0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4VPP0

No associated diseases with A4VPP0

7 regional properties for A4VPP0

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 337 - 504 IPR000795
domain Small GTP-binding protein domain 340 - 496 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 262 - 312 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 61 - 95 IPR013575
domain Translation initiation factor IF- 2, domain 3 614 - 727 IPR023115
domain Translation initiation factor IF-2, domain II 512 - 606 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTQVTVKELA QVVDTPVERL LQQMREAGLS HTSAEQVVTD NEKQALLAHL KSSHGAKVDE
70 80 90 100 110 120
PRKITLQRKT TTKLKVGGSK TISVEVRKKK TFVKRSAEEI EAEQRRELEE QRAAEEAARL
130 140 150 160 170 180
KAEQEARERA EEEARRQAEA AKAQTAETAA PAAAESASSA EPAQVVAAVE AAAPAPERKK
190 200 210 220 230 240
EEPRRVEKPR SDDDERRDRK HAQHRPSLKT KAPLARTVRS GEDEADGFRR GGRGGKSKLK
250 260 270 280 290 300
KRNQHGFQSP TGPVVREVSI GETITVAELA QQMSVKAAEV IKFMFKMGSP VTINQVLDQE
310 320 330 340 350 360
TAQLVAEELG HKVKLVSDNA LEEQLAELLK FEGESVARAP VVTVMGHVDH GKTSLLDYIR
370 380 390 400 410 420
RAKVAVGEAG GITQHIGAYH VETERGMVTF LDTPGHAAFT AMRARGAKAT DIVILVVAAD
430 440 450 460 470 480
DGVMPQTQEA VQHAKAAGVP IVVAVNKIDK PEANPDNIKN GLAALDVIPE EWGGDTPFIP
490 500 510 520 530 540
VSAKVGTGVD ELLEAVLLQA EILELKATPS APGRGVVVES RLDKGRGPVA TVLVQDGTLR
550 560 570 580 590 600
QGDMVLCGVN FGRVRAMLDE NGKPVKEAGP AIPVEILGLD GTPEAGDDLT VVADEKKARE
610 620 630 640 650 660
VALFRQGKFR EVKLARAHAG KLENIFETMG QDEKKTLNIV LKADVRGSLE ALQGSLNGLG
670 680 690 700 710 720
NDEVQVRVVG GGVGGITESD ANLALASNAV LFGFNVRADA GARKIVEAEG LDMRYYNVIY
730 740 750 760 770 780
DIIEDVKKAL TGMLGSDVRE NILGIAEVRD VFRSPKFGAI AGCMVTEGMV HRNRPIRVLR
790 800 810 820 830
DDVVIFEGEL ESLRRFKDDV AEVRAGMECG IGVKSYNDVK VGDKIEVFEK VEVARSL