A4TE29

PR
Gene name
ppk
Protein name
Polyphosphate kinase
Names
ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase
Species
Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain PYR-GCK))
KEGG Pathway
mgi:Mflv_4223
EC number
2.7.4.1: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-73 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4TE29

Entry ID Method Resolution Chain Position Source
AF-A4TE29-F1 Predicted AlphaFoldDB

No variants for A4TE29

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4TE29

No associated diseases with A4TE29

4 regional properties for A4TE29

Type Name Position InterPro Accession
domain Polyphosphate kinase middle domain 167 - 366 IPR024953
domain Polyphosphate kinase N-terminal domain 52 - 158 IPR025198
domain Polyphosphate kinase C-terminal domain 2 550 - 714 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 377 - 543 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEAQTRTEP SESSESSEAV APAITSAADS APEAPPATTA PAIENPLPED RYLNRELSWL
70 80 90 100 110 120
DFNARVLALA ADPSLPLLER AKFLAIFASN LDEFYMVRVA GLKRRDEMGL SVRSADGLSP
130 140 150 160 170 180
REQLRRISER TQQIASRHAH VFLDSVRPAL ADEGIVIVTW AQLDDAERAK LSTYFHEQVF
190 200 210 220 230 240
PVLTPLAVDP AHPFPFVSGL SLNLAITVKH PDDGGQHFAR IKVPDNVDRF VELPARGDSP
250 260 270 280 290 300
GVVRFLPMEE LIAAFLTVLF PGLEIVEHHA FRITRNADFE VEEDRDEDLL QALERELARR
310 320 330 340 350 360
RFGSPVRLEV SDDMTESMLE LLLRELDVAP GDVVEVPGLL DLSSLWQIYS VDRPGLKDPP
370 380 390 400 410 420
FVPATPSAFG ERETPKSIFS ALRDGDVLVH HPYDSFSTTV QRFIEQAAAD PNVLAIKQTL
430 440 450 460 470 480
YRTSGDSPIV NALIDAAEAG KQVVALVEIK ARFDEQANIK WARALEQAGV HVVYGLIGLK
490 500 510 520 530 540
THCKTCLVVR REGSTIRRYC HIGTGNYNPK TARLYEDIGL LTAAPDIGAD LTDLFNSLTG
550 560 570 580 590 600
YSRKESYRNL LVAPYGVRRG IIERIDREIA ATRDGAEGRI RLKANALVDE QVIDALYRAS
610 620 630 640 650 660
QAGVQVEVVV RGICALRPGE PGFSDNITVR SILGRFLEHS RIIHFRAIDE YWIGSADMMH
670 680 690 700 710 720
RNLDRRVEVM AQVKDPRLTT QLNDIFDSAA DPRTRCWELG SDGHWTALPQ EGHSVRDHQI
SLMERRRHP