A4TA35

PR
Gene name
katG
Protein name
Catalase-peroxidase
Names
CP, Peroxidase/catalase
Species
Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain PYR-GCK))
KEGG Pathway
mgi:Mflv_3451
EC number
1.11.1.21: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4TA35

Entry ID Method Resolution Chain Position Source
AF-A4TA35-F1 Predicted AlphaFoldDB

No variants for A4TA35

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4TA35

No associated diseases with A4TA35

4 regional properties for A4TA35

Type Name Position InterPro Accession
domain Haem peroxidase 95 - 422 IPR002016-1
domain Haem peroxidase 414 - 738 IPR002016-2
binding_site Peroxidases heam-ligand binding site 272 - 282 IPR019793
active_site Peroxidase, active site 104 - 115 IPR019794

Functions

Description
EC Number 1.11.1.21 Peroxidases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDTSDARPP HSDAKTASNS ESENPAIDSP EPKSHAPLTN RDWWPEQVDV SVLHKQNEKG
70 80 90 100 110 120
NPFGEDFDYA AEFAKLDVDA FKADVIDLIR TSQDWWPADY GNYAGLFVRM SWHAAGTYRI
130 140 150 160 170 180
FDGRGGAGQG SQRFAPLNSW PDNANLDKAR RLLWPIKQKY GNKISWADLI AYAGNAALEQ
190 200 210 220 230 240
SGFKTAGFAF GREDIWEPEE MLWGQEDTWL GTDKRYGGSN DDKRELAEPF GATTMGLIYV
250 260 270 280 290 300
NPEGPEGKPD PLAAAHDIRE TFGRMAMNDE ETAALIVGGH TLGKTHGAAD VNVGPEPEGA
310 320 330 340 350 360
PMEQQGLGWK CPFGTGNGND TVTSGLEVIW TGTNSQWSNA FLENLYGNEW ELTKSPAGAW
370 380 390 400 410 420
QFEAKNAEAT IPDPFGGPPR KPTMLVTDVA MREDPIYGQI TRRWLDHPEE MDAAFAKAWF
430 440 450 460 470 480
KLMHRDMGPV SRYLGPWVPA EQEIWQDPVP AVDHALIDES DIAALKSQVL QSGLSVPQLV
490 500 510 520 530 540
KTAWASAASF RGTDKRGGAN GARLRLEPQR NWEANEPAEL DKVLPVLEKI QQDFNSTATG
550 560 570 580 590 600
GKKVSLADVI VLAGSAAVEK AAKDGGYEIT VHFAPGRTDA TQESTDVESF AVLEPRTDGF
610 620 630 640 650 660
RNFFRPGDKN PLEQQLVERA YLLDLTAPEL TALIGGLRAL GANHGGSKHG VFTDKPGVLS
670 680 690 700 710 720
NDFFLNLLDM RTEWKPSELS ENVFDGKDRA TGETKWTATA NDLVFGSNSV LRALAEVYAQ
730 740
DDNQGKFVED FVAAWVKVMN NDRFDLKQ