A4SY78

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Polynucleobacter asymbioticus (strain DSM 18221 / CIP 109841 / QLW-P1DMWA-1) (Polynucleobacter necessarius subsp. asymbioticus)
KEGG Pathway
pnu:Pnuc_1227
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

201-348 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4SY78

Entry ID Method Resolution Chain Position Source
AF-A4SY78-F1 Predicted AlphaFoldDB

No variants for A4SY78

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4SY78

No associated diseases with A4SY78

7 regional properties for A4SY78

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 418 - 585 IPR000795
domain Small GTP-binding protein domain 421 - 577 IPR005225
domain Translation initiation factor IF-2, N-terminal 3 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 343 - 393 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 61 - 99 IPR013575
domain Translation initiation factor IF- 2, domain 3 694 - 810 IPR023115
domain Translation initiation factor IF-2, domain II 593 - 687 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATTVKVLAK ELKRTAPDLL EQLKAAGIEK GSEDDSITEK DKTVLLEHLQ KEHGSAETGA
70 80 90 100 110 120
RKKITLIKRE NSEIRQADSA GRTRTVQVEV RKKRVLVKRS DEAAALEVEE APAKVIAPTE
130 140 150 160 170 180
PVKSILSAEE LEKRAAEATR QAELLARQEA EMKAAEEARQ KEVAAPVVEK EEKPVDNAPD
190 200 210 220 230 240
AAATAAEKKA TADKAAKDLA ATKEKELADI RVRRAAAEAE ALAIRDMMSA PARVLKAPSE
250 260 270 280 290 300
IAAEEAKKGT LHKPAKPEGA DDKKKAVAKV GGKTIKSAET SSTWQEEGAK KPGGLKTRGD
310 320 330 340 350 360
SSGGVGGWRS GGGRKKQRQI AEANVDTNFQ VPTEPVVRDV HVPETITVAE LAHAMAVKSA
370 380 390 400 410 420
EVIKLLMGMG QMVTINQVLD QDTAMIIVEE MGHTAHAAKL DDPDLDLGTD GHDAELLPRP
430 440 450 460 470 480
PVVTVMGHVD HGKTSLLDKI RAAKVATGEA GGITQHIGAY HVETPRGMIT FLDTPGHEAF
490 500 510 520 530 540
TAMRARGAKA TDIVILVVAA DDGVMPQTKE AIHHALAGGV PIVVAINKID KPEANSERVK
550 560 570 580 590 600
TELVAEQVVP EEYGGDVPFI PVSAKTGEGI DALLENVLLQ AEILELKAAK DAPAQGLVIE
610 620 630 640 650 660
ARLDKGKGPV ATILVQSGTL KRGDMLLAGS TYGRVRAMLD ENGKPCNEAG PSIPVEIQGL
670 680 690 700 710 720
GDVPAAGESV QVVPDERKAR EIALFRQGKF RDVKLAKQQA FKLETMMENM EEGAVEAKLL
730 740 750 760 770 780
PVIIKADVQG SQEALAQSLM KLSTPEVKVQ IVHAGVGGIT ETDVNLAVAS KAVIFGFNSR
790 800 810 820 830 840
ADAAARKLAE NNGVDIRYHN IIYDAVDEVK LALSGMLTPD KKEEITGLVE IRQVFLVSKV
850 860 870 880 890 900
GAIAGCLVVD GIVKRTSSVR LLRDNVVIWT GELDSLKRFK DDAKEVRAGV ECGLSLKGYN
910
DIKEGDQLEV FEVTEVARSL