A4SPM2

PR
Gene name
nagB
Protein name
Glucosamine-6-phosphate deaminase
Names
GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase
Species
Aeromonas salmonicida (strain A449)
KEGG Pathway
asa:ASA_2828
EC number
3.5.99.6: In other compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

117-195 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4SPM2

Entry ID Method Resolution Chain Position Source
AF-A4SPM2-F1 Predicted AlphaFoldDB

No variants for A4SPM2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4SPM2

No associated diseases with A4SPM2

2 regional properties for A4SPM2

Type Name Position InterPro Accession
domain Glucosamine/galactosamine-6-phosphate isomerase 17 - 229 IPR006148
conserved_site Glucosamine-6-phosphate isomerase, conserved site 125 - 143 IPR018321

Functions

Description
EC Number 3.5.99.6 In other compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
glucosamine-6-phosphate deaminase activity Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+).

3 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
N-acetylglucosamine metabolic process The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
N-acetylneuraminate catabolic process The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLIPLKSAS QVGLWSARYI VDRINGFKPT ADRPFVLGLP TGGTPLNTYK RLIELHKAGE
70 80 90 100 110 120
VSFEHVATFN MDEYVGLPED HPESYHSFMH NNFFCHIDIR PENINILNGN AEDLVAECKR
130 140 150 160 170 180
YEDKIKSYGK INLFMGGVGN DGHIAFNEPA SSLSSRTRVK TLTEDTRIAN SRFFGGDMEQ
190 200 210 220 230 240
VPKLALTVGV GTLMDAEEIM ILVTGHGKAQ ALQAAVEGSV NHMWTISTLQ LHPKGMMVCD
250 260
EPSTMELKVK TVRYFQQLEA ANIGRL