A4SJR5

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Aeromonas salmonicida (strain A449)
KEGG Pathway
asa:ASA_1010
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

34-333 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4SJR5

Entry ID Method Resolution Chain Position Source
AF-A4SJR5-F1 Predicted AlphaFoldDB

No variants for A4SJR5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4SJR5

No associated diseases with A4SJR5

7 regional properties for A4SJR5

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 398 - 567 IPR000795
domain Small GTP-binding protein domain 401 - 556 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 323 - 373 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 62 - 100 IPR013575
domain Translation initiation factor IF- 2, domain 3 674 - 788 IPR023115
domain Translation initiation factor IF-2, domain II 574 - 667 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAEVSVKQLA TDIDTPVDRL LQQFVDAGIS KSKADDLVSE SEKQTLLAHL KKQHGGDELT
70 80 90 100 110 120
APARMTLQRK TKSTISVQGT GGKNKEVQVE VRKTRTYVKR SALEDEQRQA EAEETARLEA
130 140 150 160 170 180
EEKARSEAEN KVRLDAEEKA RREAEQARRE AEEKARIEAQ SKARQAPQPA KAASSTAQQE
190 200 210 220 230 240
AEKMAKREAE ELKRQQEQTA LQKAEELAAK KAEEARLMAE QNGPRWAEEE AARAKESSDY
250 260 270 280 290 300
HLTTNKHAQA AEDELDRKEE TSRRTAAAAV KAPKKAGRRE DDRDSRNPRA RKGKRGKMAM
310 320 330 340 350 360
PNAMKHGFNK PAAVVNRDVV IGETITVAEL ANKMAVKGVE VIKAMMKMGA MATINQVIDQ
370 380 390 400 410 420
ETAQLVAEEM GHKVVLRREN ELEEAVLSDR DETSEAKSRA PVVTIMGHVD HGKTSLLDYI
430 440 450 460 470 480
RKAKVAAGEA GGITQHIGAY HVETDSGMIT FLDTPGHAAF TSMRARGAKS TDIVVLVVAA
490 500 510 520 530 540
DDGVMPQTIE AIQHAKAAEV PIVVAVNKID KPEADPDRVK TELARYNVMS EDWGGDSQFV
550 560 570 580 590 600
HVSAKSGEGI DDLLEAILIQ SEVLELKAVV DGMASGVVIE SFLDKGRGPV ATVLVQEGTL
610 620 630 640 650 660
RQGDIVLCGL EYGRIRAMRD ELGREIKEAG PSLPVEILGL SGVPSAGDEA TVVRDEKKAR
670 680 690 700 710 720
EVALYRQGKF RDVKLARQQK AKLENMFANM TEGEVSEVNV VIKADVQGSV QAICDALVQL
730 740 750 760 770 780
STDEVKVKIV GSGVGGITET DATLAAASSA ILVGFNVRAD ASARKVIESE SLDLRYYSVI
790 800 810 820 830 840
YDLIDEVKQA MSGKLAPEYR QEIIGLAEVR SVFKSPKFGA VAGCMVTEGV VKRSNRIRVL
850 860 870 880 890
RDNVVIYEGE LESLRRFKDD VNEVRNGYEC GIAVKNYNDV REGDQIEVYE TIEIQRTL