A4SCI7

PR
Gene name
pyrG
Protein name
CTP synthase
Names
Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase
Species
Chlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))
KEGG Pathway
pvi:Cvib_0173
EC number
6.3.4.2: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

513-594 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4SCI7

Entry ID Method Resolution Chain Position Source
AF-A4SCI7-F1 Predicted AlphaFoldDB

No variants for A4SCI7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4SCI7

No associated diseases with A4SCI7

3 regional properties for A4SCI7

Type Name Position InterPro Accession
domain CTP synthase, N-terminal 8 - 272 IPR017456
domain Glutamine amidotransferase 310 - 534 IPR017926
domain CTP synthase GATase domain 298 - 534 IPR033828

Functions

Description
EC Number 6.3.4.2 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
CTP synthase activity Catalysis of the reaction: ATP + UTP + glutamine + H20= ADP + phosphate + CTP + glutamate.
glutaminase activity Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARPKNVKYV FVTGGVVSSL GKGILSASLG MLLKSRGLRV AIQKYDPYIN VDPGTMSPYQ
70 80 90 100 110 120
HGEVYVTDDG AETDLDLGHY ERFLNESTSQ ASNLTMGRVY KSVIDKERRG AYLGGTVQVV
130 140 150 160 170 180
PHVIDEIKDR LAELAKNGNY DVIITEIGGT IGDIESLPFL EAMRQMKLDM GDRNLLNIHL
190 200 210 220 230 240
TFVPYIRAAS ELKTKPTQHS VKMLLETGIQ PDILVCRSEK PLSSEIKRKV GHFCNVNNLD
250 260 270 280 290 300
VIGLNDCDTI YEVPLTLLQE QLDLRVLKKL GLKKFKEPDL VYWREFCNKV KHPTSGEVTI
310 320 330 340 350 360
VVCGKYTEYP DAYKSILEAF IHAGASNDVK VHVRLIGAEA AENEAYDFAR ELEGVHGILV
370 380 390 400 410 420
APGFGDRGIE GKVAFIRYAR EQGIPFFGIC LGMQCASVEF ARNVCNLAEA NSTEFNKRAR
430 440 450 460 470 480
YPVIDLMEQQ KKVKEKGGTM RLGSYPCIIK EGTKANEVYG KFLINERHRH RFEFNNAYRE
490 500 510 520 530 540
TFEEHGMVFS GTSPNGELVE IIEIKDHPWF VAVQFHPELK SRVQAVHPLF HGFVGAAKSY
550 560 570 580 590
AAVGHQPELA AIEPHFMPEP TAEAYAAYSE ESSAESKSFF PDNGGHDEER DSGQ