A4RK80
Gene name |
PRP28 (MGG_01583) |
Protein name |
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 |
Names |
|
Species |
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae) |
KEGG Pathway |
mgr:MGG_01583 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A4RK80
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A4RK80-F1 | Predicted | AlphaFoldDB |
No variants for A4RK80
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A4RK80 | |||||
No associated diseases with A4RK80
5 regional properties for A4RK80
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 413 - 421 | IPR000629 |
| domain | Helicase, C-terminal | 519 - 666 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 281 - 480 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 276 - 507 | IPR014001 |
| domain | RNA helicase, DEAD-box type, Q motif | 257 - 285 | IPR014014 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| nucleic acid binding | Binding to a nucleic acid. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
| RNA splicing | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPLDLEEIL | KKHKAAKAEA | AKPRFIPRGQ | RKKMEEEKKL | KVEEEQKRQQ | EELQKTRSEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QKAREELAGL | QRVRRQEQSR | SRESDHSVPT | GPRAMRSYDD | DSFNGNGNGS | NSNRNNNNNQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RDRQDASTKT | NGSRTAEEVQ | EEKKYLERYT | GPPAKVSTFS | ANKKRRRTTD | QKFNFDWDPK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DDTSQPWRYE | ETGAHERSAN | GATEQVRRKK | ATRDYNDPRL | VPWQDKELSQ | MTTRDWRLFK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VNLEIVTKGN | NIPNPMRFWE | ESNLPHVLKD | TIKQVGYTEP | TPVQRAAIPI | ALQCRDLIGI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SKTGSGKTAA | FVLPMLSYIE | PLPPLNEVTK | TEGPYALILA | PTRELATQIQ | AEVIKFATRM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GFTVVCLIGN | KRTIEEDAFA | LRNGAEIIVA | TPGRLVDCLE | RHLLVLSQCS | YVVLDEADRM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VDGGFEDSIH | KILAALPPSN | GKPDDRDAED | PNIMSKFLTP | NLRYRQTVMY | SATMPPSVER |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IAKNYLKHPA | MVTIGTIGEA | VDTVEQQAMW | VVSEDERRNK | LRAMLNTYGT | GKLVIVFVNT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KSNCDAVAKD | LKSSSFSAVT | LHGNKTQDQR | EAALQSFRDG | RTNVLVATDV | AARGLDIPDV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SLVINFNMAG | TIEVYTHRIG | RTGRAGKEGM | AITFCGPEDH | GVLYHLKQIM | SKSQMSKVPP |
| 670 | |||||
| WLKDHPEAQS | KPTF |