Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A4RD93

Entry ID Method Resolution Chain Position Source
AF-A4RD93-F1 Predicted AlphaFoldDB

No variants for A4RD93

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4RD93

No associated diseases with A4RD93

2 regional properties for A4RD93

Type Name Position InterPro Accession
domain Adenylate kinase, active site lid domain 168 - 203 IPR007862
conserved_site Adenylate kinase, conserved site 122 - 133 IPR033690

Functions

Description
EC Number 2.7.4.3 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
  • Cytoplasm, cytosol
  • Mitochondrion intermembrane space
  • Predominantly mitochondrial
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitochondrial intermembrane space The region between the inner and outer lipid bilayers of the mitochondrial envelope.

2 GO annotations of molecular function

Name Definition
adenylate kinase activity Catalysis of the reaction: ATP + AMP = 2 ADP.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

4 GO annotations of biological process

Name Definition
ADP biosynthetic process The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.
AMP metabolic process The chemical reactions and pathways involving AMP, adenosine monophosphate.
ATP metabolic process The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGAMEDQLQR LGSVLDSLDA RVKKLEQHPT LGGGSSTAQE IRMILIGPPG AGKGTQAPKI
70 80 90 100 110 120
KEKFSCCHLA TGDMLRSQVA KKTPLGREAK KIMDQGGLVS DDIVIGMIKE ELDTNVECKG
130 140 150 160 170 180
GFILDGFPRT VPQAQSLDAM LQARNQKLQH AVELQIDDAL LVARITGRLV HPASGRSYHT
190 200 210 220 230 240
TFNPPKKAMT DDVTGEPLIQ RSDDNADALK KRLATYHSQT APVVDYYRKT GIWKPIDASQ
250 260 270
EPGTVWKSLL NIFDGDAKKA SSAGGGILDK LAASGR