Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A4R6K8

Entry ID Method Resolution Chain Position Source
AF-A4R6K8-F1 Predicted AlphaFoldDB

No variants for A4R6K8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4R6K8

No associated diseases with A4R6K8

2 regional properties for A4R6K8

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 240 - 397 IPR001251
domain CRAL/TRIO, N-terminal domain 140 - 189 IPR011074

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Endoplasmic reticulum membrane ; Peripheral membrane protein
  • Microsome membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
phosphatidylinositol transfer activity Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.

1 GO annotations of biological process

Name Definition
phospholipid transport The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEAEKKATI ASGAEAAAPV AAQPPADSTA VVADASTIAV STETAQEKAG KDETPAPIAA
70 80 90 100 110 120
IAEPAASEAA AAPEESAPAA AAVVPKEPAA ASEETKAPAA ETAATPAPAA ATSAAPEATK
130 140 150 160 170 180
EKDAADAPAA AEKTGVAKLW EVCQAHEHKE IWGVTLQDPS SDVPTEIVLT KFLNANDGDV
190 200 210 220 230 240
PKAVDQLTKT LDWRNKMKPL ELLKKSFSRA KFGGLGYVTN HSEAADSKDP ALKEVFTWNI
250 260 270 280 290 300
YGNVKSMEET FGDLQQFIEW RVALMELALQ ELNIAGASAP HTITAENDPY KIYQVHDYKS
310 320 330 340 350 360
ISFLRQPASV KAASKETISV FSTVYPELLK EKFFVNVPVV MGFMYGLMKL FVAPKTLKKF
370 380 390 400
HPMSDGGALA REFGGSKVKT LGDAMPKEYG GKGEELKATG KETMLD