Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A4R5S9

Entry ID Method Resolution Chain Position Source
AF-A4R5S9-F1 Predicted AlphaFoldDB

No variants for A4R5S9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4R5S9

No associated diseases with A4R5S9

5 regional properties for A4R5S9

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 162 - 501 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 68 - 146 IPR004365
domain Aminoacyl-tRNA synthetase, class II 184 - 503 IPR006195
domain Lysyl-tRNA synthetase, class II, C-terminal 177 - 503 IPR018149
domain Lysine-tRNA ligase, class II, N-terminal 67 - 174 IPR044136

Functions

Description
EC Number 1.11.1.21 Peroxidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGECPLRTAN VAGGGTRNRD WWPNTLKLNI LRQHTEATNP YDPNFDYAEA FKSLDYEGLK
70 80 90 100 110 120
KDLRALMTDS QEYWPADFGH YGGLFVRMAW HSAGTYRVMD GRGGGGQGQQ RFAPLNSWPD
130 140 150 160 170 180
NVSLDKARRL LWPIKQKYGN KISWADLMLL TGNVALEDMG FKTFGFAGGR PDTWEADEST
190 200 210 220 230 240
YWGGETTWLG NEVRYSSGNE GHKESGVIDG SESKKGHKDI HTRDLEKPVS AAHMGLIYVN
250 260 270 280 290 300
PEGPDGIPDP VAAARDIRTT FSRMAMNDEE TVALIAGGHT VGKTHGAAPS DNVGPEPEAA
310 320 330 340 350 360
PIENQGLGWS NKHGSGKGPD TITSGLEVIW TKEPAKFTMN YLEYLFKYEW ELTKSPAGAN
370 380 390 400 410 420
QWVAKNAEEF IPDAFDPSKK HKPRMLTTDL SLRFDPEYEK ISRRFLENPE QFKDAFARAW
430 440 450 460 470 480
FKLLHRDMGP RSRWLGPEVP KETLLWEDPI PTPDHPIIDG SDVDSLKKAI LATGVAPSKL
490 500 510 520 530 540
IQTAWASAST FRGGDKRGGA NGARIRLEPQ NKWEVNNPQQ LAEVLKALEG VKADFEKSGK
550 560 570 580 590 600
KVSIADLIVL AGVAAVEQAA GVPVPFTPGR GDATQEQTDV ESFTHLEPAA DAFRNYGKGT
610 620 630 640 650 660
SRVTTEQIMV DRAQQLTLTA PELTVLVGGL RVLGANYDGS SHGVWTDKPG KLTNDFFVTL
670 680 690 700 710 720
LDPYTSWKSV DGEVFEGTNS KSGKKLTGTR ADLVFGSHSE LRALAEVYGS ADGQQKFTKD
730 740
FVAAWDKVMN LDRFDVRRGI YDETRLKSKL