A4QGM2
Gene name |
larC |
Protein name |
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein |
Names |
P2TMN nickel insertion protein, Nickel-pincer cofactor biosynthesis protein LarC |
Species |
Corynebacterium glutamicum (strain R) |
KEGG Pathway |
cgt:cgR_2381 |
EC number |
4.99.1.12: Other lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A4QGM2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A4QGM2-F1 | Predicted | AlphaFoldDB |
No variants for A4QGM2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A4QGM2 | |||||
No associated diseases with A4QGM2
No regional properties for A4QGM2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A4QGM2 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 4.99.1.12 | Other lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| lyase activity | Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. |
| nickel cation binding | Binding to a nickel (Ni) cation. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein maturation | Any process leading to the attainment of the full functional capacity of a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGLWIDATAG | VAGDMLLGAL | IDAGAELEKI | QQVVEAVIPG | DVLLRAEEVV | RQGQRGIKLH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VEAQHEHHHH | RHLSTIKELL | VNADIPEQTK | QDALGVFELI | AIAEGKVHGI | DPEKIHFHEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GAWDSIADIV | GVCEAIRQLN | PGLIAASPIA | LGFGRIKAAH | GDIPVPVPAV | AELVKGWPTQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TGALMESTEP | VGELATPTGV | ALIRHFATQD | GPFPGGIINE | VGIGAGTKDT | AGRPNVVRAV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LFSTSGKAAS | NPDTRTLVQL | EANVDDQDPR | LWTGVIESLL | VAGAVDAWLT | PILMKKGRPA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HTVSALVDSS | AVEAVKTALF | ASTTTFGIRS | WEVEREGLDR | RFEQVEVDGH | TINIKIGSRN |
| 370 | 380 | 390 | |||
| GHDISAQPEF | EDIRSAAVAL | GISEREVVAR | IPQGTTE |