A4Q8G1

PR
Gene name
nagA
Protein name
Alpha-N-acetylgalactosaminidase
Names
Glycosyl hydrolase family 109 protein
Species
Tannerella forsythia (Bacteroides forsythus)
KEGG Pathway
EC number
3.2.1.49: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-75 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4Q8G1

Entry ID Method Resolution Chain Position Source
AF-A4Q8G1-F1 Predicted AlphaFoldDB

No variants for A4Q8G1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4Q8G1

No associated diseases with A4Q8G1

3 regional properties for A4Q8G1

Type Name Position InterPro Accession
domain Gfo/Idh/MocA-like oxidoreductase, N-terminal 53 - 175 IPR000683
conserved_site Twin-arginine translocation pathway, signal sequence 1 - 30 IPR006311
conserved_site Twin-arginine translocation pathway, signal sequence, bacterial/archaeal 4 - 30 IPR019546

Functions

Description
EC Number 3.2.1.49 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
alpha-N-acetylgalactosaminidase activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.

1 GO annotations of biological process

Name Definition
metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MENTRRNFLK KVTAAGIGAA GLAVTDQAMA AVNQPGEAAQ QKKKPAGKSD GMLRFGFIGT
70 80 90 100 110 120
GSRCQEHINN VLGIQGNKIV AICDIQKGPL EKTLKHIAKF NVPEPKVYTG GEREFEKMLN
130 140 150 160 170 180
NEEFDCVIIA SPWEWHVPMA VAAMKAGVPY VGVEVSAANT VEECWDLVNV SEATGSHLNI
190 200 210 220 230 240
LENVCYRRDV MAALRMVREG LFGEMIHGTC GYQHDLRDVK FNDGIHYTYQ EGGELRMGPT
250 260 270 280 290 300
AYAEAQWRTQ HSVTRNGDIY PTHGIGPVAN CLNINRGNRF LSLTSMATQS RGLHNFVVDK
310 320 330 340 350 360
GGANHPYAKI HFNLGDIVTS MIKCANGQTV IVTHDTNLPR PYSLGFRIQG TRGLWMNDGN
370 380 390 400 410 420
HVYVEGQSKP HRWDASDDWF KKYDHKLWST LELKAKEAGH GGMDYIMMYD FIDAIRNKKP
430 440 450 460
TPMDCYDAAA WSAISGLSEM SIARGGAVVD FPDFTRGQWI HRQPAFAL