A4JGV5

PR
Gene name
ppc
Protein name
Phosphoenolpyruvate carboxylase
Names
PEPC, PEPCase
Species
Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia (strain R1808))
KEGG Pathway
bvi:Bcep1808_2510
EC number
4.1.1.31: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-91 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4JGV5

Entry ID Method Resolution Chain Position Source
AF-A4JGV5-F1 Predicted AlphaFoldDB

No variants for A4JGV5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4JGV5

No associated diseases with A4JGV5

2 regional properties for A4JGV5

Type Name Position InterPro Accession
active_site Phosphoenolpyruvate carboxylase, Lys active site 203 - 214 IPR018129
active_site Phosphoenolpyruvate carboxylase, His active site 640 - 652 IPR033129

Functions

Description
EC Number 4.1.1.31 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoenolpyruvate carboxylase activity Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.

3 GO annotations of biological process

Name Definition
carbon fixation A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).
oxaloacetate metabolic process The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKSSGSARTA RRNAALPSTD AQTGALATVA NGRAKPATKP KDSIRQTKRT TKAAGASKPA
70 80 90 100 110 120
ARTREDKDGP LFEDIRFLGR LLGDVVREQE GDTVFDVVET IRQTAVKFRR EDDSQAAQTL
130 140 150 160 170 180
EKKLRKLTPE QTVSVVRAFS YFSHLANIAE DRHHNRRRRI HALAGSAPQP GTVAYALEQL
190 200 210 220 230 240
KTSGNASKRV LQRFFDDALI VPVLTAHPTE VQRKSILDAQ HDIARLLAER DQPLTARERA
250 260 270 280 290 300
YNESMLRARV TALWQTRMLR DARLTVGDEI ENALSYYRTT FLDELPALYG DIEAALAEHG
310 320 330 340 350 360
LPARVPAFFQ MGSWIGGDRD GNPNVTAATL DEAINRQAAV ILEHYLEQVH KLGAELSVSN
370 380 390 400 410 420
LLVGANDAVK ALAAASPDQS PHRVDEPYRR ALIGIYTRLA ASARVRLGEG TVPVRSAGRG
430 440 450 460 470 480
APPVRAVPYA DSEAFVADLK VLTASLEEHH GASLAAPRLT PLMRAAEVFG FHLSSIDLRQ
490 500 510 520 530 540
SSDIHEAVVA ELFARAGVHA DYASLSEDDK LIALLAALAD PRPLRSPYIE YSALAQSELG
550 560 570 580 590 600
VFEKAREVRA QFGPRAVRNY IISHTETVSD LVEVLLLQKE TGLLEGAFGA AHDSARNGLM
610 620 630 640 650 660
VIPLFETIPD LRDAARIMRE YFALPGIEAL IAHQGAEQEV MLGYSDSNKD GGFLTSNWEL
670 680 690 700 710 720
YRAELALVDL FRDRKITLRL FHGRGGTVGR GGGPTYQAIL SQPPGTVNGQ IRLTEQGEVI
730 740 750 760 770 780
ASKFANPEIG RRNLETVVAA TLEASLLPQS NAPAQLPAFE AAMQALSDAA MASYRALVYE
790 800 810 820 830 840
TPGFTDYFFA ATPITEIAEL NIGSRPASRK LQDPKNRRIE DLRAIPWGFS WGQCRLLLTG
850 860 870 880 890 900
WYGFGSAVSA YLDGAPDAAA RTKRVALLKK MNKTWPFFAN LLSNMDMVLA KTDLAVASRY
910 920 930 940 950 960
AQLVADRKLR KHVFERIVAE WERTAQALAE ITGHEGRLAT NPLLARSIKN RFPYLDPLNH
970 980 990
LQVELIKRHR AGDTNARLRR GIHLTINGIA AGLRNTG