A4J108
Gene name |
fusA |
Protein name |
Elongation factor G |
Names |
EF-G |
Species |
Desulforamulus reducens (strain ATCC BAA-1160 / DSM 100696 / MI-1) (Desulfotomaculum reducens) |
KEGG Pathway |
drm:Dred_0212 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A4J108
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A4J108-F1 | Predicted | AlphaFoldDB |
No variants for A4J108
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A4J108 | |||||
No associated diseases with A4J108
9 regional properties for A4J108
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Elongation factor EFG, domain V-like | 599 - 686 | IPR000640 |
| domain | Translational (tr)-type GTP-binding domain | 8 - 282 | IPR000795 |
| domain | Translation elongation factor EFTu-like, domain 2 | 322 - 389 | IPR004161 |
| domain | Small GTP-binding protein domain | 9 - 180 | IPR005225 |
| domain | Translation elongation factor EFG/EF2, domain IV | 477 - 597 | IPR005517 |
| domain | Elongation factor G, domain III | 403 - 478 | IPR009022 |
| conserved_site | Tr-type G domain, conserved site | 51 - 66 | IPR031157 |
| domain | EFG, domain V | 602 - 679 | IPR035649 |
| domain | Elongation Factor G, domain II | 402 - 475 | IPR041095 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation elongation factor activity | Functions in chain elongation during polypeptide synthesis at the ribosome. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARQFPLERT | RNIGIMAHID | AGKTTTTERI | LFYTGRVHKI | GEVHDGAATM | DWMVQEQERG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ITITSAATTA | QWNGHRVNII | DTPGHVDFTV | EVERSLRVLD | GAVAVFCSVG | GVEPQSETVW |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RQADKYGVPR | LAYINKMDRV | GADFFNGMDM | IKNRLGANPV | AIQLPIGSED | RFKGIVDLVT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KKAIVYIDDL | GTNSETTDIP | ADMVDQVEEY | REKLLEAVAE | SDEELMMKYL | EGEELTEEEI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KVAIRKATLA | VKITPVICGS | SFKNKGVQSL | LDAIVDYLPA | PTDVPPIQGV | NPDTGTEDQR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ISSDNEPFAA | LAFKIMTDPY | VGKLSYFRVY | SGTLKSGSYV | LNSTKGKKER | VGRILQMHAN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HREEIPEVYA | GDIAAAVGLK | DTTTGDTLCD | EKSLIILESM | EFPDPVIHVA | IEPKTKADQD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KMGVALSKLS | EEDPTFKVRT | DEETGQTIIA | GMGELHLEII | VDRLLREFKV | QANVGRPQVA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YKETIRKAVK | AEGKFVRQSG | GKGQYGHVWI | ELEPLEAGGP | GYEFVNKIVG | GVVPREYIAP |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VDNGIKEAME | NGILAGYQMV | DIKATLYDGS | YHEVDSSEMA | FKIAGSMAFK | NGAQKANPVL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LEPIFKVEVT | VPEEYMGDVI | GDLNSRRGRI | EEMGQRGNAR | IVSAFVPLAE | MFGYATDLRS |
| 670 | 680 | 690 | |||
| KTQGRGTYSM | QHDHYEEVPK | NIAEGIIAKR | KG |